Outcomes after resection of pancreatic ductal adenocarcinoma remain highly variable, and existing prognostic models lack sufficient accuracy. Here, the authors aimed to improve survival prediction by integrating transcriptome‐based subtyping into a validated clinical model and applying it to a multicenter real‐world cohort of fresh‐frozen resection ...
Marjolein F. Lansbergen +20 more
wiley +1 more source
Synthesis, crystal structure determination, Hirshfeld surface and crystal void analyses, inter-action energy calculations and energy frameworks of (3a<i>RS</i>,4<i>RS</i>,9a<i>RS</i>)-2-benzyl-3-oxo-2,3,3a,4,9,9a-hexa-hydro-1<i>H</i>-benzo[<i>f</i>]iso-indole-4-carb-oxy-lic acid. [PDF]
Alekseeva KA +6 more
europepmc +1 more source
Half a Century of Per‐ and Polyfluoroalkyl Substances in Northern Gannet Eggs: Impact of Regulations
ABSTRACT Per‐ and polyfluoroalkyl substances (PFAS), known as “forever chemicals”, are persistent organic pollutants that have been widely used in the industry across the globe for many decades. Their chemical stability, bioaccumulation, and toxicity pose major environmental and health risks. This study examines temporal trends in the concentrations of
Anaïs Fournier +2 more
wiley +1 more source
ABSTRACT Diisononyl phthalate (DINP) is a high molecular weight phthalate and high production volume chemical. DINP's carcinogenic potential has been investigated in four rodent bioassays, with liver tumors observed in three of the studies. Authoritative assessments have hypothesized that DINP acts through the peroxisome proliferator‐activated receptor
Amanda N. Buerger +3 more
wiley +1 more source
The crystal structure of (3<i>Z</i>)-4-[(3-hy-droxy-phen-yl)amino]-pent-3-en-2-one: helices and π-stacking inter-actions of hy-dro-gen-bridged rings. [PDF]
Syed J, Hadzovic A.
europepmc +1 more source
ABSTRACT Bystander intervention is widely assumed to foster workplace inclusion, yet no studies have directly examined this relationship. Through abductive qualitative analysis of 53 interviews across two contrasting organisations—a consulting firm and a remote mine site—we investigate how bystander intervention relates to workplace inclusion for ...
Laura Jennings +4 more
wiley +1 more source
Synthesis, crystal structure and Hirshfeld surface analysis of 4-(3-hy-droxy-6-meth-oxy-4-oxo-4<i>H</i>-chromen-2-yl)benzaldehyde. [PDF]
Snizhko AD +3 more
europepmc +1 more source
Insights into [(2-phen-oxy-phen-yl)lithium(THF)(TMEDA)] and diphenyl ether: structural influence of metalation on the aromatic system. [PDF]
Nuss M, Schrimpf T, Strohmann C.
europepmc +1 more source
Synthesis and structure of (<i>Z</i>)-8-methyl-2-(8-methyl-2,3,4,9-tetra-hydro-carbazol-1-yl-idene)-2,3,4,9-tetra-hydro-carbazol-1-one. [PDF]
Sridharan M, Thiruvalluvar AA.
europepmc +1 more source

