Results 161 to 170 of about 180,219 (298)

From Inflammatory Bowel Disease to Cancer: Gut Microbiota–Immune Microenvironment Crosstalk and Natural Product‐Based Therapeutic Opportunities

Cancer Nexus, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD), primarily Crohn's disease and ulcerative colitis, is a chronic relapsing inflammatory disorder of the gastrointestinal tract and an important risk factor for IBD‐associated cancer. Increasing evidence suggests that gut microbiota dysbiosis, epithelial barrier dysfunction, and immune microenvironment remodeling
Xue Zhang, Chongchong Gao, Rui Jiang, Zijian Wu, Jian Bai   +4 more
wiley   +1 more source

The Varied Presentation of Appendiceal Mucinous Neoplasms: A Rural Case Series. [PDF]

Cureus
Vu D, Pajtak R, Strauss P.
europepmc   +1 more source

Tuning the Growth Pattern of Triangular Silver Nanoplates from Lateral to Vertical by Secondary Metal Addition

ChemPhysChem, Volume 26, Issue 6, March 15, 2025.
What happens, if in the synthesis of flat silver platelets, the slow deposition of silver along twinning faults is disturbed by the addition of a nobler metal? We have looked into it and found a way to fine‐tune the metal deposition in lateral and vertical direction.
Jonas Kluitmann, Andrea Csáki, Wolfgang Fritzsche, Johann Michael Köhler   +3 more
wiley   +1 more source

Diagnostic Usefulness of Serum CA 125 in Patients with Ovarian Cancer

, 1985
Serum CA 125 (an antigen common to most nonmucinous epithelial ovarian carcinoma) were measured in patients with gynecologic disease. CA 125 levels were elevated (34U/ml or higher) in 77.8% (7/9) of ovarian cancer patients.
Takahashi, Kentaro, Fukuda, Sumio, Kitao, Manabu, Yoshino, Kazuo, Shibukawa, Toshihiko, Murao, Fuminori   +5 more
core  

Analysis of prognostic factors in ovarian clear cell carcinoma: a retrospective cohort study. [PDF]

Transl Cancer Res
Xie X, Wei Y, Liu C, Li S, Chen W.
europepmc   +1 more source

A Systematic Review on Disease‐Modifying Therapies in Parkinsonian Disorders

Clinical Pharmacology &Therapeutics, EarlyView.
Parkinsonian disorders, including Parkinson's disease, Lewy body dementia, multiple system atrophy, and progressive supranuclear palsy, are progressive neurodegenerative conditions with no treatment options to slow disease progression. This systematic review provides an overview of evidence of disease‐modifying therapies that have been evaluated in ...
Pepijn P.N.M. Eijsvogel, Lars M.G. Smits, Philip H.C. Kremer, Geert Jan Groeneveld   +3 more
wiley   +1 more source

Specificity and affinity of 26 monoclonal antibodies against the CA 125 antigen: First report from the ISOBM TD-1 workshop

, 1996
The specificity of 26 monoclonal antibodies against the CA 125 antigen was investigated in two phases of the ISOBM TD-1 workshop. The binding specificity was studied using CA 125 immunoextracted by specific antibodies immobilized on various solid phases,
Nilsson, O, Hilgers, J, OBrien, TJ, deBruijn, HWA, Vitali, A, Clark, J, Jette, D, Nustad, K, Shigemasa, K, Sakahara, H, Gadnell, M, Kreutz, FT, Endo, K, Bormer, OP, Nozawa, S, Warren, D, Karlsson, B, Kenemans, P, Bast, RC, Saga, T, Paus, E, Hammarstrom, S, Seguin, P, Suresh, MR   +23 more
core  

Superiority of the ROMA index over HE4 and CA125 for diagnosing ovarian cancer in a Bangladeshi cohort. [PDF]

Clinics (Sao Paulo)
Das PK, Hossain S, Rahman AFMA, Saha P, Ahmed S, Mustakim TM, Tanjim KF, Chowdhury AK, Jishan TR, Tabassum T.   +9 more
europepmc   +1 more source

Payload‐Based Clinical Pharmacology Review of Approved Antibody–Drug Conjugates: Commonalities and Considerations for Streamlined Development

Clinical Pharmacology &Therapeutics, EarlyView.
Antibody–drug conjugates (ADCs) combine the specificity of an antibody with the potency of a cytotoxic drug. Thirteen ADCs, utilizing seven unique cytotoxic payloads and targeting 11 distinct antigens, are currently approved by the US Food and Drug Administration as of June 2025, representing a rapidly growing and highly promising class of anticancer ...
Sijie Lu, Qingqing Xiao, Lixuan Qian, Siyuan Sun, Zhu Zhou, Michael Z. Liao, Chunze Li   +6 more
wiley   +1 more source

OMIP‐121: Immune Phenotyping of Canine Peripheral Leukocytes by Mass Cytometry

Cytometry Part A, EarlyView.
ABSTRACT Dogs are a critical non‐rodent species used in preclinical safety studies, particularly, in the pharmaceutical field, due to their physiological, metabolic, and immunological similarities to humans. As such, immunophenotyping of canine peripheral blood mononuclear cells (PBMCs) plays a crucial role in translational research, immune monitoring,
Huyen Thuc Tran Luong, Dominique Revets, Sofie Vercammen, Ario de Marco, Hilde de Rooster, Antonio Cosma   +5 more
wiley   +1 more source