Results 61 to 70 of about 1,191,068 (306)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The Significance of Carbohydrate Antigen 19-9, Carcinoembryonic Antigen, Calcium and Zinc as Biomarkers in Sera of Colorectal Cancer Patients

مجلة بغداد للعلوم
Colorectal cancer (CRC) is a disease that begins exclusively in the colon or rectum and is caused by an abnormal proliferation of glandular epithelial cells in the colon.  Carbohydrate antigen 19-9 (CA19-9), carcinoembryonic antigen (CEA), calcium (Ca),
Fenik Ahmed Nadir, Zeyan Abdullah Ali
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Biochemical markers in cancer of the ovary : a review [PDF]

, 1990
The ideal tumour marker would be one which is detectable before obvious clinical involvement. A number of biochemical markers have been used to diagnose carcinoma of the ovary.
Cauchi, Maurice N.
core  

Alternative antibody for the detection of CA19-9 antigen: a European multicenter study for the evaluation of the analytical and clinical performance of the Access (R) GI Monitor assay on the UniCel (R) Dxl 800 Immunoassay System [PDF]

, 2008
Background: Gastrointestinal cancer antigen CA19-9 is known as a valuable marker for the management of patients with pancreatic cancer. Methods: The analytical and clinical performance of the Access(R) GI Monitor assay (Beckman Coulter) was evaluated on ...
Barone D, Bekaii-Saab TS, Dittadi R, Gogas H, Heinemann V, Ishii H, Jiang XT, Magnani JL, Micke O, Molina R, Reiter W, Reiter W, Safi F, Steinberg W, Tempero MA, Wang WS   +15 more
core   +3 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Etiology of Severe Non-malaria Febrile Illness in Northern Tanzania: A Prospective Cohort Study. [PDF]

, 2013
The syndrome of fever is a commonly presenting complaint among persons seeking healthcare in low-resource areas, yet the public health community has not approached fever in a comprehensive manner.
AJ Bouley, Anne B. Morrissey, B Nadjm, B Nadjm, B Pastorino, BM Greenwood, CA Petti, Charles Muiruri, CIR Chandler, CJ Murray, CJ Murray, DC Clifton, DR Feikin, EA Reddy, Eng Eong Ooi, Grace D. Kinabo, H Reyburn, HM Biggs, JA Berkley, JA Crump, JA Crump, JA Crump, JA Crump, John A. Bartlett, John A. Crump, JT Hertz, K Baltzell, LE Scott, LK Archibald, M Amexo, M Prabhu, Mathieu Picardeau, MD Bajani, MK Mayhood, MM Levine, N Scaramozzino, OS Levine, PA Connolly, PL Petit, R Lozano, Renee L. Galloway, Robert F. Massung, Robyn A. Stoddard, SI Hay, SJ Olsen, SL Brown, SM Graham, SM Lofgren, TJ O'Dempsey, Venance P. Maro, Wilbrod Saganda, William L. Nicholson, YL Lai   +52 more
core   +11 more sources

High Carbohydrate 19-9 Antigen Serum Levels in Patients with Nonmelanoma Skin Cancer and Primary Occult Cancer

Biomedicines, 2020
Background: Non-melanoma skin cancers (NMSC), despite having a favourable prognosis, present an increased risk of occult malignancies. The aim of this study was the evaluation of the usefulness of the mucinous marker carbohydrate 19-9 antigen (CA 19-9 ...
Giulia Malaguarnera, Saverio Latteri, Roberto Madeddu, Vito Emanuele Catania, Gaetano Bertino, Rosario Emanuele Perrotta, Francesco Dinotta, Michele Malaguarnera   +7 more
doaj   +1 more source

Clinical usefulness of cancer markers in primary breast cancer [PDF]

, 2011
The aim of this study was to investigate the diagnostic power of CA 549, MSA and CA 15-3 in identifying breast cancer. The study included 232 patients of which 56 were healthy, 43 had benign breast cancer and 191 with other growths.
Clouth, Aline, Oremek, Gerhard Maximilian, Verring, A., Ziolkowski, Piotr   +3 more
core   +2 more sources

Colorectal carcinoma: nucleosomes, carcinoembryonic antigen and ca 19-9 as apoptotic markers; a comparative study [PDF]

Journal of Biomedical Science, 2011
Colorectal carcinoma is a common and often fatal disease in which methods of early detection and monitoring are essential. The present study was conducted for measuring serum levels of nucleosomes, carcinoembryonic antigen (CEA) and CA 19-9 in patients newly diagnosed with colorectal carcinoma and confirmed by clinicopathological study.Thirty subjects ...
Mahgoub Samir S, Al-Shuneigat Jehad M, Huq Fazlul   +2 more
openaire   +3 more sources