Results 41 to 50 of about 42,942 (233)

The diagnosis and pathological value of combined detection of HE4 and CA125 for patients with ovarian cancer

Open Medicine, 2016
To evaluate the value of individual and combined measurement of human epididymis protein 4 (HE4) and cancer antigen 125 (CA-125) in the diagnosis of ovarian cancer.
Zheng Li-e, Qu Jun-ying, He Fei
doaj   +1 more source

Urinary CE-MS peptide marker pattern for detection of solid tumors [PDF]

, 2018
Urinary profiling datasets, previously acquired by capillary electrophoresis coupled to mass-spectrometry were investigated to identify a general urinary marker pattern for detection of solid tumors by targeting common systemic events associated with ...
Belczacka, Iwona, Frantzi, Maria, Jankowski, Vera, Latosinska, Agnieszka, Merseburger, Axel S., Metzger, Jochen, Mischak, Harald, Siwy, Justyna, Vlahou, Antonia   +8 more
core   +2 more sources

Systemic Inflammatory Response Markers Associated with Infertility and Endometrioma or Uterine Leiomyoma in Endometriosis

Therapeutics and Clinical Risk Management, 2020
Xuanxuan Jing,1,* Chen Li,1,2,* Jintang Sun,1 Jin Peng,3 Yu Dou,4 Xiaofei Xu,3 Chao Ma,1 Zhaogang Dong,5 Yanguo Liu,6 Hui Zhang,3 Qianqian Shao,1 Hui Zhang,7 Lijie Wang,3 Yun Zhang,1 Xun Qu1 1Institute of Basic Medical Sciences, Key Laboratory of ...
Jing X, Li C, Sun J, Peng J, Dou Y, Xu X, Ma C, Dong Z, Liu Y, Zhang H, Shao Q, Zhang H, Wang L, Zhang Y, Qu X   +14 more
doaj  

The next steps in improving the outcomes of advanced ovarian cancer [PDF]

, 2015
Worldwide ovarian cancer affects over 200,000 women per year. Overall survival rates are poor due to two predominate reasons. First, the majority of patients present with advanced disease creating significant difficulty with effecting disease eradication.
Blagden, S, Fotopoulou, C, Gabra, H, Openshaw, MR   +3 more
core   +1 more source

Differential mortality association of loop diuretic dosage according to blood urea nitrogen and carbohydrate antigen 125 following a hospitalization for acute heart failure [PDF]

, 2012
AimsRecent observations in chronic stable heart failure suggest that high-dose loop diuretics (HDLDs) have detrimental prognostic effects in patients with high blood urea nitrogen (BUN), but recent findings have also indicated that diuretics may improve ...
Ahmed, D'Aloia, Damman, Damman, Dickstein, Domanski, Doty, Eduardo Núñez, Eshaghian, Felker, Fine, Francis, Francisco J. Chorro, Gema Miñana, Gheorghiade, Gottlieb, Gregg C. Fonarow, Guglin, Hunt, Juan Sanchis, Julio Núñez, Kishimoto, Levy, Lindenfeld, Mullens, Mullens, Nieminen, Núñez, Núñez, Núñez, Patricia Palau, Pau Llàcer, Peacock, Pilar Merlos, Royston, Royston, Sands, Schrier, Silvia Ventura, Testani, Testani, Vicent Bodí, Vicente Bertomeu-González, Yilmaz   +43 more
core   +1 more source

B4GALNT4‐Mediated Glycosylation of PDK1 Activates the PI3K‐AKT Signaling Pathway to Promote Prostate Cancer Progression

Advanced Science, EarlyView.
This study identifies B4GALNT4 as a key driver of prostate cancer (PCa). It shows that B4GALNT4 glycosylates PDK1 protein at the N531 site, which stabilizes the PDK1 and constitutively activates the PI3K‐AKT pathway. This mechanism promotes tumor cell proliferation, migration, and invasion. The findings establish the B4GALNT4‐PDK1 glycosylation axis as
Shaoqin Jiang, Mengqiang Li, Qingfu Su, Ruiling Dou, Shaoshan Lin, Jili Zhang, Xiaochen Sun, Haolan Yu, Wei Bao, Min Qu, Yan Wang, Chenghua Yang, Xu Gao   +12 more
wiley   +1 more source

Analyzing the Role of CA125 in the Care of Patients with Epithelial Ovarian Cancer [PDF]

Batna Journal of Medical Sciences
Background: Ovarian cancer is the most lethal gynecological malignancy, often diagnosed at advanced stages due to asymptomatic presentation. The CA125 tumor marker plays a crucial role in the diagnosis and management of this disease.
Dalal ZERROUK, Habiba HEMAMID, Nadji BOUGHABA, Hichem El Azhari BENMAMAR, Youcef KHENCHOUL, Ines BOUKERZAZA, Taha FILALI   +6 more
doaj   +1 more source

EPCAM+CD45+ cells in ascitic fluid of patients with ovarian cancer: a relationship with tumor marker levels and tumor grade

Сибирский онкологический журнал, 2022
Purpose of the study: to assess the relationship between atypical/hybrid forms of EpCAM+CD45+ cells in ascitic fluid of ovarian cancer patients and the levels of cancer markers, such as CA125 and HE4, and the tumor grade. Material and methods.
A. V. Kozik, E. V. Kaigorodova, M. Yu. Grishchenko, S. V. Vtorushin, A. L. Chernyshova   +4 more
doaj   +1 more source

Congenital imperforate hymen with hydrocolpos and hydronephrosis associated with severe hydramnios and increase of maternal ovarian steroidogenic enzymes [PDF]

, 2010
This is a clinical research paperStudy Objective: To study clinical features of patient presented with severe hydramnios, associated with hydronephrosis, that was antenatally diagnosed and has been successfully treated immediately after birth.
Foster, H, Goumenou, A, Karamouti, M, Karteris, E   +3 more
core   +1 more source

A Protein‐Centric Strategy Coupled with Match‐Between‐Run Glycoproteomics Enables Discovery of Robust Site‐Specific Glycan Biomarkers for Hepatocellular Carcinoma

Advanced Science, EarlyView.
In this study, a highly robust N‐glycoproteomics (HRN) platform with a newly developed match‐between‐run scheme is used for biomarker discovery. This study proposes a protein‐centric strategy to prioritize proteins susceptible to aberrant glycosylation.
Lei Liu, Taiheng Ma, Qi Liu, He Zhu, Zheng Fang, Jiahong Ma, Ting Yu, Yan Wang, Jiahua Zhou, Xiaoyan Liu, Yaqian Li, Zhimou Guo, Xinmiao Liang, Mingming Dong, Deguang Sun, Mingliang Ye   +15 more
wiley   +1 more source