Results 41 to 50 of about 43,558 (239)

The Potential Role of MUC16 (CA125) Biomarker in Lung Cancer: A Magic Biomarker but with Adversity

Diagnostics, 2022
Lung cancer is the second most commonly diagnosed cancer in the world. In terms of the diagnosis of lung cancer, combination carcinoembryonic antigen (CEA) and cancer antigen 125 (CA125) detection had higher sensitivity, specificity, and diagnostic odds ...
Hebatallah M. Saad, Ghada F. Tourky, Hayder M. Al-kuraishy, Ali I. Al-Gareeb, Ahmed M. Khattab, Sohaila A. Elmasry, Abdulrahman A. Alsayegh, Zaki H. Hakami, Ahmad Alsulimani, Jean-Marc Sabatier, Marwa W. Eid, Hazem M. Shaheen, Ali A. Mohammed, Gaber El-Saber Batiha, Michel De Waard   +14 more
doaj   +1 more source

Congenital imperforate hymen with hydrocolpos and hydronephrosis associated with severe hydramnios and increase of maternal ovarian steroidogenic enzymes [PDF]

, 2010
This is a clinical research paperStudy Objective: To study clinical features of patient presented with severe hydramnios, associated with hydronephrosis, that was antenatally diagnosed and has been successfully treated immediately after birth.
Foster, H, Goumenou, A, Karamouti, M, Karteris, E   +3 more
core   +1 more source

CA125: Holy Grail or a Poisoned Chalice [PDF]

Nephron Clinical Practice, 2005
The history of (and perhaps the lessons to be learned from) peritoneal CA125 investigation presents no better example of the diffi culties in assigning the status of a ‘marker’ predictive of membrane dysfunction to factors measured in dialysis effl uent. In 1995, Visser et al. [3] were the fi rst to suggest that CA125 could be used as ‘a bulk marker of
Nicholas, Topley, Daryn, Michael, Timothy, Bowen   +2 more
openaire   +2 more sources

Analyzing the Role of CA125 in the Care of Patients with Epithelial Ovarian Cancer [PDF]

Batna Journal of Medical Sciences
Background: Ovarian cancer is the most lethal gynecological malignancy, often diagnosed at advanced stages due to asymptomatic presentation. The CA125 tumor marker plays a crucial role in the diagnosis and management of this disease.
Dalal ZERROUK, Habiba HEMAMID, Nadji BOUGHABA, Hichem El Azhari BENMAMAR, Youcef KHENCHOUL, Ines BOUKERZAZA, Taha FILALI   +6 more
doaj   +1 more source

A Binding Domain on Mesothelin for CA125/MUC16 [PDF]

Journal of Biological Chemistry, 2009
Ovarian cancer and malignant mesothelioma frequently express both mesothelin and CA125 (also known as MUC16) at high levels on the cell surface. The interaction between mesothelin and CA125 may facilitate the implantation and peritoneal spread of tumors by cell adhesion, whereas the detailed nature of this interaction is still unknown.
Osamu, Kaneko, Lucy, Gong, Jingli, Zhang, Johanna K, Hansen, Raffit, Hassan, Byungkook, Lee, Mitchell, Ho   +6 more
openaire   +2 more sources

MEOX1 Coordinates Autocrine‐Paracrine Programs via SPHK1/S1P to Promote Lymph Node Metastasis in Ovarian Cancer

Advanced Science, EarlyView.
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li, Xiuling Zhi, Qianhan Lin, Yating Sun, Yihua Sun, Zulimire Abudousalamu, Mengyang Xue, Chang Zheng, Xiaotian Li, Liangqing Yao, Mo Chen   +10 more
wiley   +1 more source

A real-world comparison of the clinical and economic utility of OVA1 and CA125 in assessing ovarian tumor malignancy risk

Journal of Comparative Effectiveness Research, 2023
Aim: This largest-of-its-kind study evaluated the clinical utility of CA125 and OVA1, commonly used as ovarian tumor markers for assessing the risk of malignancy.
Gerard P Reilly, David A Gregory, Dennis J Scotti, Samuel Lederman, Wade A Neiman, Steven Sussman, Lisa M Bean, Mercedes M Ekono   +7 more
doaj   +1 more source

Effects of GnRH Agonist and Dienogest in Combination on HE4 and CA125 Levels in Patients with Adenomyosis and Adenomyoma: A Prospective Cohort Study

Clinical and Experimental Obstetrics & Gynecology, 2023
Background: The traditional pathology of adenomyosis (AM) suggests that this is a common benign uterine disease. Hysterectomy is the gold standard of care and is viewed as a decisive treatment for AM; however, more conservative treatment approaches are ...
DongGe Wang, LiMei Ji, CenLin Jia, MingJun Shao   +3 more
doaj   +1 more source

Integrating Radiomics and Computational Pathology to Predict Early Recurrence of Pancreatic Ductal Adenocarcinoma and Uncover Its Biological Basis in Tumor Microenvironment

Advanced Science, EarlyView.
Accurate prediction of early recurrence in pancreatic ductal adenocarcinoma is vital for optimizing treatment. A novel, integrated radiomics‐pathology machine learning model successfully forecasts recurrence risks by analyzing preoperative CT images and computational pathology.
Sihang Cheng, Fuze Cong, Shenbo Zhang, Rui Lv, Wenjia Zhang, Xinyi Ke, Juncheng Wu, Zhonghe Zhao, Kui Zhao, Di Dong, Ruofan Zhang, Zhengyu Jin, Max Seidensticker, Zhiwei Wang, Huanwen Wu, Xianlin Han, Nan Hong, Huadan Xue   +17 more
wiley   +1 more source

Experience and Lessons Learned in the Treatment of Transforming Small Cell Neuroendocrine Carcinoma of the Prostate: A Case Report and Literature Review

Case Reports in Oncology
Introduction: Small cell neuroendocrine carcinoma of the prostate (SCNECP) is a rare and highly malignant tumor that commonly transforms into conventional prostate adenocarcinoma (CPAC).
Binbin Song, Yan Luo, Qing Li, Hong Pan, Dong Li   +4 more
doaj   +1 more source