A Pilot Study to Develop a Diagnostic Test for Pancreatic Ductal Adenocarcinoma Based on Differential Expression of Select miRNA in Plasma and Bile [PDF]
OBJECTIVES: Accurate peripheral markers for the diagnosis of pancreatic ductal adenocarcinoma (PDAC) are lacking. We measured the differential expression of select microRNAs (miRNAs) in plasma and bile among patients with PDAC, chronic pancreatitis (CP),
Cote, Gregory A. +6 more
core +1 more source
Mesoporous Materials for Electrochemical Biosensors: From Broad Structure to Silica Film
This review showcases how mesoporous materials advance biosensing, spanning from material classes and fabrication strategies to the unique role of silica films as functional sensing platforms. With tunable porosity, high surface area, and versatile chemistry, these materials enhance selectivity and signal amplification in biosensors.
Vinh Khanh Ho +3 more
wiley +1 more source
Neoadjuvant Docetaxel-Based Chemoradiation for Resectable Adenocarcinoma of the Pancreas [PDF]
International audienceTo assess the safety and efficacy of a new neoadjuvant chemoradiation (CRT) docetaxel-based regimen in patients with resectable adenocarcinoma of the pancreatic head or ...
Azria, David +8 more
core +3 more sources
CA19–9 decrease and survival according to platelet level in patients with advanced pancreatic cancer
Background CA19–9 decrease during treatment has been associated with superior survival of pancreatic cancer in several studies. The evidence to show the correlation of high platelet level with inferior survival is insufficient in pancreatic cancer.
Y. Chen +3 more
doaj +1 more source
Targeted therapy of advanced gallbladder cancer and cholangiocarcinoma with aggressive biology: eliciting early response signals from phase 1 trials. [PDF]
PurposePatients with advanced cholangiocarcinoma (CC) and gallbladder carcinoma (GC) have few therapeutic options for relapsed disease. methods: Given the overall poor prognosis in this population and the availability of novel targeted therapies, we ...
Falchook, Gerald S +14 more
core +2 more sources
Novel Liquid Biopsy in Gastrointestinal Cancers
ABSTRACT Gastrointestinal (GI) cancers represent a significant global health burden, being among the leading causes of cancer‐related deaths. The prognosis for patients remains unsatisfactory, largely because most cancers are detected at advanced stages.
Li‐Chun Chang +2 more
wiley +1 more source
Background: Although Carbohydrate antigen 19-9 (CA19-9) is considered clinically useful and informative for pancreatic carcinoma (PC), false positive results, and false negative results have restricted its clinical use.
Ailing Zhong +14 more
doaj +1 more source
Cancer biomarkers detection using microstructured protein chip: implementation of customized multiplex immunoassay [PDF]
Protein chips have demonstrated to be a sensitive and low cost solution to identify and detect tumor markers. However, efficient multiparametric analysis remains a challenge due to protein variability.
Chevolot, Yann +5 more
core +1 more source
Ciliated hepatic foregut cyst: A report of 6 cases and a review of the English literature [PDF]
BACKGROUND: Ciliated hepatic foregut cyst (CHFC) is a rare cystic lesion most commonly identified in segment 4 of the liver that arises from the embryonic foregut.
Bishop, Katherine C +3 more
core +2 more sources
Pancreatic Neuroendocrine Tumor Leading to a Diagnosis of Multiple Endocrine Neoplasia Type 1
ABSTRACT Pancreatic neuroendocrine neoplasms are rare but occasionally encountered. They are generally highly vascularized solid tumors, often round in shape with clear boundaries, defined contours, and a homogeneous internal structure. However, they can also present with atypical features, such as cystic degeneration, hemorrhage, calcification, and ...
Noriyuki Hirakawa +9 more
wiley +1 more source

