Results 81 to 90 of about 34,423 (243)

Mirrizi Syndrome and Markedly Elevated Levels of Carbohydrate Antigen 19-9 in the Absence of Malignant Disease

open access: yesCase Reports in Gastrointestinal Medicine, 2017
Elevated carbohydrate antigen 19-9 (CA19-9) beyond 1000 U/L occurs in nonneoplastic conditions which is causing questioning of the use of CA19-9 as a marker for screening.
Natasha Shah   +3 more
doaj   +1 more source

Evidence-Based Detection of Pancreatic Canc [PDF]

open access: yes, 2020
This study is an effort to develop a tool for early detection of pancreatic cancer using evidential reasoning. An evidential reasoning model predicts the likelihood of an individual developing pancreatic cancer by processing the outputs of a Support ...
Chandratre, Rajeshwari Deepak
core   +1 more source

Head‐to‐head comparison of the diagnostic value of fecal and serum carcinoembryonic antigen for colorectal cancer detection

open access: yesInternational Journal of Cancer, EarlyView.
What's New? The diagnostic value of fecal versus serum carcinoembryonic antigen (CEA) for colorectal cancer detection remains unclear. This study provides a head‐to‐head comparison of serum and fecal CEA using matched samples from two large colorectal cancer screening studies and two fecal sample processing methods.
Xianzhe Li   +10 more
wiley   +1 more source

Prognostic Value of Changes in Preoperative and Postoperative Serum CA19-9 Levels in Gastric Cancer

open access: yesFrontiers in Oncology, 2020
Objective: The prognostic significance of serum CA19-9 levels in gastric cancer patients remains a matter debate. The aim of this study was to determine the prognostic value of changes in preoperative and postoperative serum CA19-9 levels in patients ...
Xiao-Hai Song   +19 more
doaj   +1 more source

Dynamics of the association between circulating levels of miRNA and pancreatic cancer risk through the years prior to pancreatic cancer diagnosis

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Early diagnosis is critical for improving pancreatic ductal adenocarcinoma prognosis, but few biomarkers currently exist. In a case–control study of 1,307 pancreatic cancer cases and matched pairs nested in prospective cohort studies, 13 miRNA–cancer associations were found to change during the blood‐draw‐to‐diagnosis time window.
Hui Cai   +10 more
wiley   +1 more source

Cholestasis is the Main Determinant of Abnormal CA 19–9 Levels in Patients with Liver Cirrhosis

open access: yesThe International Journal of Biological Markers, 2000
Background/Aims Altered CA19–9 levels are commonly found in patients with liver cirrhosis though a clear explanation for this finding has not yet been given.
E. Giannini   +13 more
doaj   +1 more source

Bioinorganic Site‐Specific Conjugation of Multi‐Arm Linkers to Create Pharmaceuticals With Targeting and Effector Functions

open access: yesJournal of the Chinese Chemical Society, EarlyView.
This Account showcases a modular, multi‐arm linker platform that decouples payload loading from antibody conjugation. By leveraging a computationally designed ACPGHA zinc‐binding motif, we demonstrate the construction of homogeneous antibody‐drug conjugates and theranostic antibody‐radionuclide conjugates with high payload loading. The multi‐arm linker
Cédric Grauffel   +2 more
wiley   +1 more source

Y-box protein-1/p18 fragment identifies malignancies in patients with chronic liver disease [PDF]

open access: yes, 2011
Background Immunohistochemical detection of cold shock proteins is predictive for deleterious outcome in various malignant diseases. We recently described active secretion of a family member, denoted Y-box (YB) protein-1.
Frank Tacke   +7 more
core   +2 more sources

Independent Prognostic Value of Natural Tooth Count Versus Posterior Teeth Occlusion in Resected Pancreatic Cancer

open access: yesJournal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background/Purpose Prognostic significance of preoperative patient‐related factors, including oral health status, in pancreatic ductal adenocarcinoma (PDAC) remains unclear. We evaluated the association between preoperative factors—particularly oral health parameters—and long‐term survival after curative PDAC resection.
Kaoru Seo   +8 more
wiley   +1 more source

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