Results 71 to 80 of about 5,917,592 (236)

Prognostic Value of Changes in Preoperative and Postoperative Serum CA19-9 Levels in Gastric Cancer

open access: yesFrontiers in Oncology, 2020
Objective: The prognostic significance of serum CA19-9 levels in gastric cancer patients remains a matter debate. The aim of this study was to determine the prognostic value of changes in preoperative and postoperative serum CA19-9 levels in patients ...
Xiao-Hai Song   +19 more
doaj   +1 more source

Comparative study of CA242 and CA19-9 in chronic pancreatitis [PDF]

open access: yesBritish Journal of Cancer, 1996
CA242 has been proved to be useful in the diagnosis of pancreatic cancer. The aim of the present study was to clarify the mechanisms contributing to the high specificity of CA242 as compared with CA19-9 resulting from scarce serum elevation of this antigen in patients with chronic pancreatitis by correlating serum levels and endoscopic retrograde ...
N, Furuya   +6 more
openaire   +2 more sources

Prognostic Determinants of Overall Survival After Resection for Pancreatic Ductal Adenocarcinoma: A Consensus‐Based Conceptual Framework

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) carries a dismal prognosis despite surgical resection, yet the prognostic literature remains fragmented across hundreds of single‐institution studies that vary in design, covariates, and analytical approaches.
Muhammad Maisam Ali   +8 more
wiley   +1 more source

Mass Spectrometry‐Based Extracellular Vesicle Proteomics for Biomarker Discovery

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicle (EV) proteomics has emerged as a powerful platform for decoding intercellular communication and advancing biomarker discovery across human diseases. EVs carry proteins that reflect their cells of origin, offering a minimally invasive window into physiological and pathological processes.
Ya‐Juan Liu, Juan Peng, Chao Kang
wiley   +1 more source

Diagnostic Role of CA19-9, CA19-9/CRP Ratio and CA19-9/Total Bilirubin Ratio in Differentiating Benign and Malignant Obstructive Jaundice

open access: yesBangladesh Journal of Medicine
Background: Serum carbohydrate antigen (CA19-9) is a tumour marker which is significantly elevated in biliary and pancreatic malignancy. It is also increased in some benign conditions associated with jaundice. So many strategies have been recommended to improve the power of CA 19-9 to differentiate benign and malignant obstructive jaundice.
Mohammad Golam Azam   +5 more
openaire   +1 more source

CA19-9 serum levels predict micrometastases in patients with gastric cancer [PDF]

open access: yes, 2016
Background. We explored the prognostic value of the up-regulated carbohydrate antigen (CA19-9) in node-negative patients with gastric cancer as a surrogate marker for micrometastases. Patients and methods.
Mojca Plankl   +9 more
core   +1 more source

Apo10 and TKTL1 as novel liquid biopsy biomarkers for early detection of gastrointestinal malignancies

open access: yesVIEW, EarlyView.
(A) Overview of the study population and schematic illustration showing tumor‐derived apoptotic and metabolic biomarkers, Apo10 and TKTL1, being phagocytosed by circulating monocytes and subsequently detected in peripheral blood. (B) Illustration of the epitope detection in monocytes (EDIM) strategy, using a flow‐cytometric gating approach based on ...
Zhiying Mao   +8 more
wiley   +1 more source

Improving tumor marker comparability: A case series on harmonizing carbohydrate antigen 19‐9 and carbohydrate antigen 15‐3 measurements across diverse measurement systems

open access: yesVIEW, EarlyView.
CA19‐9 and CA15‐3 measurements from seven contemporary immunoassay systems were compared using 464 and 499 native serum samples, respectively. Inter‐system correlations were higher for CA15‐3 than for CA19‐9, and only a limited number of systems met biological variation‐derived bias criteria.
Jia Li   +10 more
wiley   +1 more source

Mirrizi Syndrome and Markedly Elevated Levels of Carbohydrate Antigen 19-9 in the Absence of Malignant Disease

open access: yesCase Reports in Gastrointestinal Medicine, 2017
Elevated carbohydrate antigen 19-9 (CA19-9) beyond 1000 U/L occurs in nonneoplastic conditions which is causing questioning of the use of CA19-9 as a marker for screening.
Natasha Shah   +3 more
doaj   +1 more source

A CA19-9-PRODUCING GASTRIC CANCER

open access: yesNihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association), 2010
症例は81歳,男性.2007年5月黒色便を主訴に来院した.上部消化管内視鏡検査で胃体中部小弯に3型病変を認め,生検で中分化型腺癌であった.腫瘍マーカーは,血清CA19-9値656U/mlと著明な高値を認めた.胃癌cStage IBの術前診断で幽門側胃切除術を行った.手術時,病変は漿膜に浸潤し,2カ所の肝転移巣を認め,fStage IVであり治癒切除困難であった.標本の免疫組織学染色で,癌細胞の細胞質,間質にCA19-9の強陽性所見を認めた.術後一時的に血清CA19-9値79.5U/mlと低下したが,術後3カ月には血清CA19-9値の再上昇と共に,多発皮膚転移,肺転移をきたし,術後6カ月で永眠された.
AISU, Naoya   +5 more
openaire   +2 more sources

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