Results 51 to 60 of about 4,240,909 (230)

Label-free multiplex immunoassay of AFP, CEA and CA19-9 by integrated microfluidic biosensor based on imaging ellipsometry

, 2016
This study describes the development of alpha-fetoprotein (AFP), carcinoembryonic antigen (CEA) and carbohydrate 19-9(CA19-9) multiplex immunoassay by integrated microfluidic device based on imaging ellipsometry (IMBIE). Different strategies for AFP, CEA
Zhang ST, Chen N, Song FY, Yang QL, Huang, CH (reprint author), Chongqing Univ Sci & Technol, Inst Biomat & Living Cell Imaging Technol, Chongqing, Peoples R China., 靳刚, Jin, G (reprint author), Chinese Acad Sci, Inst Mech, Beijing, Peoples R China., Huang CH, Liao XL, Chen YY, Yao B, Chen, YY (reprint author), Chinese Acad Sci, Suzhou Inst Nanotech & Nanobion, Suzhou, Peoples R China.   +11 more
core   +1 more source

Cutoff value of carcinoembryonic antigen and carbohydrate antigen 19-9 elevation levels for monitoring recurrence in patients with resectable gastric adenocarcinoma

The International Journal of Biological Markers, 2009
Background The aim of this longitudinal study was to try and improve the specificity of carcinoembryonic antigen (CEA) and carbohydrate antigen (CA) 19-9 in monitoring tumor recurrence in patients with resectable gastric adenocarcinoma by setting ...
Miao-Zhen Qiu, Jun-Zhong Lin, Zhi-Qiang Wang, Feng-Hua Wang, Zhi-Zhong Pan, Hui-Yan Luo, Yu-Hong Li, Zhi-Wei Zhou, You-Jian He, Rui-Hua Xu MD, PhD   +9 more
doaj   +1 more source

Upregulation of CA 19-9 in the Mouse Kidney Following Unilateral Ureteral Obstruction [PDF]

, 2001
High serum levels of carbohydrate antigen19-9 (CA19-9) have been detected in patients with pancreatic cancer and described in several recent case reports of patients with hydronephrosis.
Aoki, Daiyu, Kanda, Shigeru, Li, Shengwen, Hayashi, Tomayoshi, Nomata, Koichiro, Kanetake, Hiroshi   +5 more
core  

CA19-9-low and Lewis(+) pancreatic cancer: A unique subtype.

, 2017
339 Background: Pancreatic cancer is a lethal malignancy and patients often survive within one year. CA19-9 is the most important biomarker for pancreatic cancer and Lewis (-) individuals have no or scarce CA19-9 secretion. We have met several patients
Xian Jun Yu, Guopei Luo
core   +1 more source

Tumor‐Derived Alpha‐1 Antitrypsin Promotes Liver Metastasis of Colorectal Cancer Through the Neutrophil Extracellular Traps–CCDC25 Pathway

Advanced Science, EarlyView.
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei, Chunning Li, Lei Zhan, Xiaoyan Li, Yan Hui, Yue Jin, Jing Zhang, Lu Yang, Xin Sun, Xiaoxi Li, Qian Dong, Jingdong Zhang   +11 more
wiley   +1 more source

Prognostic Value of Circulating CA 19-9 in Colorectal Cancer Patients [PDF]

, 2000
Aims: We examined the preoperative serum levels of sialyl Lewisa (CA19-9) and carcinoembryonic antigen (CEA) in 262 colorectal cancer patients, in order to clarify whether or not the prognostic value of CA19-9 after curative surgery is superior to that ...
Kurosaki, Nobuko, Sawai, Terumitsu, Arisawa, Kokichi, Jibiki, Masaaki, Tsuji, Takashi, Yamaguchi, Hiroyuki, Nakagoe, Tohru, Miyashita, Hiroko, Ayabe, Hiroyoshi, Ohbatake, Masayuki, Nakashima, Atsushi, Yasutake, Toru   +11 more
core  

Small Extracellular Vesicles‐Derived Circ6718 Unlocks Stromal Remodeling and Serves as a Biomarker in Gastric Cancer

Advanced Science, EarlyView.
sEVs‐circ6718 serves as a promising serum biomarker for gastric cancer early diagnosis and prognosis, promoting malignant transformation in gastric cancer cells and GC‑MSC differentiation into CAFs. sEVs‑circ6718 holds potential as a biomarker for the early diagnosis and prognostic assessment of gastric cancer.
Fan Zhang, Xueyan Zang, Dongli Wang, Rong Li, Hui Qian, Wenrong Xu, Jiajia Jiang, Yongmin Yan   +7 more
wiley   +1 more source

CEA but not CA19-9 is an independent prognostic factor in patients undergoing resection of cholangiocarcinoma

, 2017
Cholangiocarcinoma (CCA) represents a rare form of primary liver cancer with increasing incidence but dismal prognosis. Surgical treatment has remained the only potentially curative treatment option, but it remains unclear which patients benefit most ...
Longerich, Thomas, Koch, Alexander, Anne T. Schneider, Tom F. Ulmer, Tom Luedde, Schneider, Anne T., Marcel Binnebösel, Binneboesel, Marcel, Ulf P. Neumann, Christian Trautwein, Alexander Koch, Georg Lurje, Vucur, Mihael, Wenzel Schoening, Trautwein, Christian, Katja L. Kauertz, Roderburg, Christoph, Sven H. Loosen, Lurje, Georg, Tacke, Frank, Christoph Roderburg, Loosen, Sven H., Ulmer, Tom F., Frank Tacke, Kauertz, Katja L., Neumann, Ulf P., Binnebösel, Marcel, Cornelis H. Dejong, Dejong, Cornelis H., Mihael Vucur, Luedde, Tom, Schoening, Wenzel, Thomas Longerich   +32 more
core   +1 more source

PancDS in Real‐World Practice: A Prospective Multicenter Validation of a Clinical Decision‐Support System Bridging Experience Gaps in Pancreatic Lesion Diagnosis

Advanced Science, EarlyView.
A biomimetic artificial intelligence system, PancDS, has been developed to distinguish pancreatic ductal adenocarcinoma from mass‐forming pancreatitis by adaptively integrating clinical data, radiomics, and deep learning features. Validated across multicenter, reader‐study, and prospective settings, PancDS improves diagnostic accuracy, particularly for
Zhibo Wang, Weinuo Qu, Wenwen Cai, Chuhuai Wang, Chenxi Lyu, Qingguo Xie, Qian Chu, Yaqi Shen, Peng Xiao, Feng Li, Qingpeng Zhang, Jiali Li, Jeong Min Lee, Zhen Li   +13 more
wiley   +1 more source

Aptamer‐Targeted PrPC Drives Colorectal Cancer Metastasis via a LYN‐STAT3 Complex and Enables Liquid Biopsy Detection

Advanced Science, EarlyView.
The aptamer WHY‐3E identifies PrPC as a CRC driver. Stabilized by USP18, endocytosed PrPC forms a LYN/STAT3 complex, upregulating MSN transcription to promote metastasis. Crucially, WHY‐3E sensitively detects PrPC‐positive circulating exosomes, establishing a robust theoretical foundation for non‐invasive clinical diagnostics.
Chunlin Wang, Hongyu Wu, Chaojing Zheng, Hao Zhang, Xiaoqiu Wu, Jiaqi Wang, Zewen Chang, Jun Xiang, Yunxiao Liu, Chenkai Zhang, Yuliuming Wang, Hao Jiang, Yuchen Zhong, Jun Luo, Ying Chen, NaNa Zhang, Weiyuan Zhang, Ziming Yuan, ChaoXia Zou, Weihong Tan, Meng Wang, Hanqing Hu, Tao Bing, Guiyu Wang   +23 more
wiley   +1 more source