Results 31 to 40 of about 37,527 (263)

Prognostic Impact of Presurgical CA19-9 Level in Pancreatic Adenocarcinoma: A Pooled Analysis

Translational Oncology, 2019
BACKGROUND: Presurgical carbohydrate antigen 19-9 (CA19-9) level predicts overall survival (OS) in resected pancreatic adenocarcinoma (PaC). The aim of this pooled analysis was to evaluate if presurgical CA19-9 level can also predict local control (LC ...
Gian Carlo Mattiucci, Alessio G. Morganti, Francesco Cellini, Milly Buwenge, Riccardo Casadei, Andrea Farioli, Sergio Alfieri, Alessandra Arcelli, Federica Bertini, Felipe A. Calvo, Silvia Cammelli, Lorenzo Fuccio, Lucia Giaccherini, Alessandra Guido, Joseph M. Herman, Gabriella Macchia, Bert W. Maidment, III, Robert C. Miller, Francesco Minni, William F. Regine, Michele Reni, Stefano Partelli, Massimo Falconi, Vincenzo Valentini   +23 more
doaj   +1 more source

Low-Dose Continuous 5-Fluorouracil Combined with Leucovorin, nab-Paclitaxel, Oxaliplatin, and Bevacizumab for Patients with Advanced Pancreatic Cancer: A Retrospective Analysis. [PDF]

, 2018
BackgroundContinuous-infusion 5-fluorouracil (5FU) and calcium leucovorin plus nab-paclitaxel and oxaliplatin have been shown to be active in patients with pancreatic cancer.
Bedford, Rudolph, Donahue, Timothy, Hines, O Joe, Hoos, William, Isacoff, William H, Rahib, Lola, Reber, Howard A, Upfill-Brown, Alexander   +7 more
core   +1 more source

Glutamine is a substrate for glycosylation and CA19-9 biosynthesis through hexosamine biosynthetic pathway in pancreatic cancer

Discover Oncology, 2023
Background Carbohydrate antigen 19–9 (CA19-9) is the most widely used biomarker for pancreatic cancer. Since CA19-9 closely correlates with patient outcome and tumor stage in pancreatic cancer, the deciphering of CA19-9 biosynthesis provides a potential ...
Chen Liu, Shengming Deng, Zhiwen Xiao, Renquan Lu, He Cheng, Jingjing Feng, Xuxia Shen, Quanxing Ni, Weiding Wu, Xianjun Yu, Guopei Luo   +10 more
doaj   +1 more source

Association between cancer antigen 19‐9 and diabetes risk: A prospective and Mendelian randomization study

Journal of Diabetes Investigation, 2020
Aims/Introduction Elevated serum cancer antigen 19‐9 (CA19‐9) levels have been found in diabetes patients in most observational studies; however, whether there is a causal association between CA19‐9 and diabetes mellitus is unclear. Materials and Methods
Zhaoyang Li, Jing Wang, Xu Han, Fei Wang, Hua Hu, Jing Yuan, Ping Yao, Sheng Wei, Huan Guo, Dan Zheng, Yuhan Tang, Handong Yang, Meian He   +12 more
doaj   +1 more source

Optimal value of CA19-9 determined by KRAS-mutated circulating tumor DNA contributes to the prediction of prognosis in pancreatic cancer patients

Scientific Reports, 2021
Despite the acceptance of carbohydrate antigen 19-9 (CA19-9) as a valuable predictor for the prognosis of pancreatic ductal adenocarcinoma (PDAC), its cutoff value remains controversial.
Fumiaki Watanabe, Koichi Suzuki, Sawako Tamaki, Iku Abe, Yuhei Endo, Yuji Takayama, Hideki Ishikawa, Nao Kakizawa, Masaaki Saito, Kazushige Futsuhara, Hiroshi Noda, Fumio Konishi, Toshiki Rikiyama   +12 more
doaj   +1 more source

Proposed carbohydrate antigen 19-9 (CA19-9) cut-off values for the detection of pancreatic cancer in patients with poorly controlled diabetes: a real-world study

Endocrine Journal, 2023
CA19-9 is a tumor marker for pancreatic cancer (PC), and the nondiabetic cut-off level is 37 U/mL. CA19-9 levels are said to rise in patients with tumors like PC and intraductal papillary mucinous neoplasm (IPMN). CA19-9 levels have also been shown to be
Taku Yamada, Taichi Minami, Masayo Yamada, Yasuo Terauchi   +3 more
doaj   +1 more source

Tumor Burden Score Stratifies Prognosis of Patients With Intrahepatic Cholangiocarcinoma After Hepatic Resection: A Retrospective, Multi-Institutional Study

Frontiers in Oncology, 2022
BackgroundThe prognostic significance of tumor burden score (TBS) on patients who underwent curative-intent resection of intrahepatic cholangiocarcinoma (ICC) has not been evaluated.
Hui Li, Rongqiang Liu, Haizhou Qiu, Yang Huang, Wenbin Liu, Jiaxin Li, Hong Wu, Genshu Wang, Dewei Li   +8 more
doaj   +1 more source

Urinary CE-MS peptide marker pattern for detection of solid tumors [PDF]

, 2018
Urinary profiling datasets, previously acquired by capillary electrophoresis coupled to mass-spectrometry were investigated to identify a general urinary marker pattern for detection of solid tumors by targeting common systemic events associated with ...
Belczacka, Iwona, Frantzi, Maria, Jankowski, Vera, Latosinska, Agnieszka, Merseburger, Axel S., Metzger, Jochen, Mischak, Harald, Siwy, Justyna, Vlahou, Antonia   +8 more
core   +2 more sources

CA19-9 elevation in ovarian mature cystic teratoma: Discrimination from ovarian cancer – CA19-9 level in teratoma [PDF]

Medical Science Monitor, 2013
We aimed to identify clinical characteristics of ovarian mature cystic teratoma (MCT) in association with CA19-9 elevation, and to determine if CA19-9 is a useful marker in discrimination of MCT from ovarian cancer (OC).Medical records of 322 women with pathologically-confirmed MCT or OC (stage 1 or 2) were reviewed retrospectively.
Cho, Hye-yon, Kim, Kidong, Jeon, Yong-Tark, Kim, Yong-Beom, No, Jae Hong   +4 more
openaire   +2 more sources

Gemcitabine: Progress in the treatment of pancreatic cancer [PDF]

, 2001
Unresectable pancreatic cancer has a dismal prognosis with a median survival of 3-5 months in untreated disease. Since the introduction of gemcitabine, pancreatic cancer may no longer be regarded a chemotherapy-resistant tumor.
Heinemann, Volker
core   +1 more source