Da-Ming Xu,1,* Ze-Wen Zhang,2,* Jing-Xing Yi,3 Long Xie,3 Wen-Jun Yu,2 Jin-Feng Qiu,4 Cheng-Wei Xu,5 Chun-Ling He,6 Xian-Ru Xu,7 Jun Yin3 1Division of Urological Surgery, The Second Affiliated Hospital of Shantou University Medical College ...
Xu DM +9 more
doaj
Exocytosis, dependent on Ca2+ release from Ca2+ stores, is regulated by Ca2+ microdomains [PDF]
The relationship between the cellular Ca2+ signal and secretory vesicle fusion (exocytosis) is a key determinant of the regulation of the kinetics and magnitude of the secretory response. Here, we have investigated secretion in cells where the exocytic response is controlled by Ca2+ release from intracellular Ca2+ stores.
Low, Jiun T. +3 more
openaire +5 more sources
The self-maintaining nature of ventricular fibrillation : contribution of L-type Ca²+ channels and Na+/Ca²+ exchange to cardiomyocyte Ca²+ overload in ventricular fibrillation : surface fluorescence study in isolated perfused rat hearts [PDF]
Approximately 40% of all deaths in Switzerland are due to cardiovascular diseases.1 An important part of these deaths happen because of life-threatening cardiac arrhythmias.
Driamov, Sergey
core +1 more source
Effect of oxytocin on free intracellular Ca2+ levels and progesterone release by human granulosa-lutein cells [PDF]
Oxytocin and its receptor are found in the corpus luteum in a variety of species, including the human. In the present study we used fura-2 microfluorimetry to investigate whether activation of the oxytocin receptor of cultured human granulosa-lutein ...
Wiemann, M. +4 more
core +1 more source
Objective. To compare the efficacy and cost-effectiveness of simple nonadherent dressings with other more expensive dressing types in the treatment of venous leg ulcers. Study Design. Retrospective cohort study. Location.
Syed M. Asim Hussain
doaj +1 more source
Endothelin-Induced Sarcoplasmic Reticulum Calcium Depletion Waves in Vascular Smooth Muscle Cells [PDF]
Agonist-stimulated waves of elevated cytoplasmic Ca2+ concentration ([Ca2+]i ) regulate blood vessel tone and vasomotion in vascular smooth muscle. Previous studies employing cytoplasmic Ca2+ indicators revealed that these Ca2+ waves were generated by a ...
Cornelis van Breemen +7 more
core +1 more source
Ca2+ releasing process and nicotinic acid adenine dinucleotide phosphate
The paper is devoted to recognizing of nicotinic acid adenine dinucleotide phosphate (NAADP) as releaser of intracellular calcium from intracellular stores.
S. Bychkova
doaj +1 more source
Thioridazine, belonging to first-generation antipsychotic drugs, is a prescription used to treat schizophrenia. However, the effect of thioridazine on intracellular Ca2+ concentration ([Ca2+]i) and viability in human liver cancer cells is unclear.
I-Shu Chen +6 more
doaj +1 more source
Ca2+ Regulation in the Na+/Ca2+ Exchanger Involves Two Markedly Different Ca2+ Sensors [PDF]
The plasma membrane Na+/Ca2+ exchanger (NCX) is almost certainly the major Ca2+ extrusion mechanism in cardiac myocytes. Binding of Na+ and Ca2+ ions to its large cytosolic loop regulates ion transport of the exchanger. We determined the solution structures of two Ca2+ binding domains (CBD1 and CBD2) that, together with an alpha-catenin-like domain ...
Hilge, M, Aelen, J, Vuister, GW
openaire +4 more sources
Subcellular heterogeneity of ryanodine receptor properties in ventricular myocytes with low T-tubule density [PDF]
Rationale: In ventricular myocytes of large mammals, not all ryanodine receptor (RyR) clusters are associated with T-tubules (TTs); this fraction increases with cellular remodeling after myocardial infarction (MI).
MacQuaide, N. +21 more
core +2 more sources

