Results 51 to 60 of about 567,581 (297)
Frontiers in Immunology, 2021 Ca2+ signaling plays an essential role in T cell activation, which is a key step to start an adaptive immune response. During the transition from a quiescent to a fully activated state, Ca2+ microdomains characterized by reduced spatial and temporal ...
Diana Gil +2 more
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Journal of Inflammation Research, 2022 Xiao-Min Zhang, Ming-Hui Lun, Wei Du, Fang Ma, Ze-Qing Huang Department of Anesthesiology, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institution, NO.44 Xiaoheyan Road, Dadong District, Shenyang, Liaoning Province, 110042 ...
Zhang XM, Lun MH, Du W, Ma F, Huang ZQ
doaj
Shigella IpaA mediates actin bundling through diffusible vinculin oligomers with activation imprint
Cell Reports, 2023 Summary: Upon activation, vinculin reinforces cytoskeletal anchorage during cell adhesion. Activating ligands classically disrupt intramolecular interactions between the vinculin head and tail domains that bind to actin filaments.
Cesar Valencia-Gallardo +17 more
doaj +1 more source
Endothelin-Induced Sarcoplasmic Reticulum Calcium Depletion Waves in Vascular Smooth Muscle Cells
, 2011 Agonist-stimulated waves of elevated cytoplasmic Ca2+ concentration ([Ca2+]i ) regulate blood vessel tone and vasomotion in vascular smooth muscle. Previous studies employing cytoplasmic Ca2+ indicators revealed that these Ca2+ waves were generated by a ...
Cornelis van Breemen +7 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A Thermodynamic Study of Complex Formation between 15-Crown-5 with Mg2+, Ca2+, Sr2+ and Ba2+ in Acetonitrile Methanol Binary Mixtures Using Conductometric Method [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 2001 The complexation reactions between Mg2+, Ca2+, Sr2+ and Ba2+ metal cations with 15-crown-5 (15C5) were studied in acetonitrile (AN)-methanol (MeOH) binary mixtures at different temperatures using conductometric method. 15C54 forms 1:1 complexes with Mg2+,
Gholam Hossein Rounaghi +1 more
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Clocks & Sleep, 2023 Achieving synchronization between the central and peripheral body clocks is essential for ensuring optimal metabolic function. Meal timing is an emerging field of research that investigates the influence of eating patterns on our circadian rhythm ...
Ahmed S. BaHammam, Abdulrouf Pirzada
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Calcium homeostasis and role of ryanodine receptor type 1 (RyR1) in immune cells [PDF]
, 2010 Ryanodine receptors are intracellular Ca2+ release channels located in the membrane of the Endoplasmatic/Sarcoplasmatic Reticulum. Ryanodine receptor 1 isoform is preferentially expressed in skeletal muscle where it is responsible for release of Ca2 ...
Vukcevic, Mirko
core +1 more source
Regulation of Ca2+ transport by sarcoplasmic reticulum Ca2+-ATPase at limiting [Ca2+]
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1999 The factors regulating Ca2+ transport by isolated sarcoplasmic reticulum (SR) vesicles have been studied using the fluorescent indicator Fluo-3 to monitor extravesicular free [Ca2+]. ATP, in the presence of 5 mM oxalate, which clamps intravesicular [Ca2+] at approximately 10 microM, induced a rapid decline in Fluo-3 fluorescence to reach a limiting ...
openaire +2 more sources