Results 41 to 50 of about 667,052 (292)

Ca2+ Regulation in the Na+/Ca2+ Exchanger Involves Two Markedly Different Ca2+ Sensors [PDF]

Molecular Cell, 2006
The plasma membrane Na+/Ca2+ exchanger (NCX) is almost certainly the major Ca2+ extrusion mechanism in cardiac myocytes. Binding of Na+ and Ca2+ ions to its large cytosolic loop regulates ion transport of the exchanger. We determined the solution structures of two Ca2+ binding domains (CBD1 and CBD2) that, together with an alpha-catenin-like domain ...
Hilge, M, Aelen, J, Vuister, GW
openaire   +4 more sources

CO2 introduced the coagulation-flocculation of oil acidized wastewater: pollutant removal and cost analysis

Water Science and Technology, 2021
It is difficult to adjust the pH of oil acidized wastewater rich in Ca2+, thus hindering the polyacrylamide (PAM) flocculation. This study aims at accelerating the flocculation process by introducing CO2 into the water to induce the formation of CaCO3 ...
Jinyi Qin, Yifan Gong, Chuan Qin, Hailong Meng, Yiwen He, Qingyang Qin, Junfa Gao   +6 more
doaj   +1 more source

Matrix-free calcium in isolated chromaffin vesicles [PDF]

, 1985
Isolated secretory vesicles from bovine adrenal medulla contain 80 nmol of Ca2+ and 25 nmol of Mg2+ per milligram of protein. As determined with a Ca2+-selective electrode, a further accumulation of about 160 nmol of Ca2+/mg of protein can be attained ...
Bulenda, D., Gratzl, Manfred
core   +1 more source

Role of cation gradients in hypercontracture of myocytes during simulated ischemia and reperfusion [PDF]

, 1993
We examined the relationship between transsarcolemmal cation gradients and hypercontracture of cardiac myocytes in ischemia and reperfusion using adult rat ventricular myocytes superfused with buffer mimicking normal or ischemic extracellular fluid ...
J. P. Navas, Marsh, J. D., R. A. Kelly, J. D. Marsh, Krämer, Bernhard K., Kelly, R. A., Nishida, M., T. W. Smith, Smith, T. W., M. Nishida, B. Kraemer, Borzak, S., S. Borzak, Navas, J. P.   +13 more
core   +1 more source

Characteristics of Ca2+, Mg2+-dependent ATP hydrolysis in sperm cells of infertile men

Біологічні студії, 2020
Disturbances of fertilizing potential of spermatozoa are closely associated with dysfunction of ion-transporting ATPases, in particular Ca2+, Mg2+-АТРase.
O. I. Meskalo, R. V. Fafula, Z. D. Vorobets   +2 more
doaj   +1 more source

Cardiac Ca2+ Signaling and Ca2+ Sensitizers

Circulation Journal, 2008
The role of Ca2+ in cardiac excitation-contraction (E-C) coupling has been established by simultaneous measurements of contractility and Ca2+ transients by means of aequorin in intact myocardium and Ca2+ sensitive fluorescent dyes in single myocytes. The E-C coupling process can be classified into 3 processes: upstream (Ca2+ mobilization), central (Ca2+
openaire   +3 more sources

Relationship between Ca2+ and cAMP as second messengers in ACTH-induced cortisol production in bovine adrenal fasciculata cells

Endocrine Journal, 2023
In adrenal fasciculata cells stimulated by ACTH, Ca2+ and cAMP play indispensable roles as second messengers in cortisol production. However, whether their second messengers cooperatively or independently participate in steroid production remains unclear.
Masahiko Kutsukake, Naoko Kuwabara, Yoshikazu Miyate, Kenzo Kudo, Shoko Goto, Eiichi Taira, Eiichi Tachikawa   +6 more
doaj   +1 more source

Intracellular zinc modulates cardiac ryanodine receptor-mediated calcium release [PDF]

, 2015
This work was supported by University of St. Andrews, Tenovus Scotland Grant T14/35 (to S. J. P.), British Heart Foundation Grant FS/14/69/31001 (to S. J.
Woodier, Jason, J. Woodier (7634894), S. J. Pitt (7634900), A. J. Stewart (7634897), Pitt, Samantha Jane, Stewart, Alan J., Rainbow, Richard D., Richard D. Rainbow (7619696), Pitt, Samantha Jane; id_orcid, Stewart, Alan J.; id_orcid   +9 more
core   +1 more source

CFTR deficiency aggravates Ang II induced vasoconstriction and hypertension by regulating Ca𝟐+ influx and RhoA/Rock pathway in VSMCs

Frontiers in Bioscience-Landmark, 2021
Background: Cystic fibrosis transmembrane conductance regulator (CFTR) has been associated with vascular tone and blood pressure (BP), however, its role in the genesis of hypertension remains elusive.
Liyan Zhao, Feng Yuan, Ni Pan, Yun Yu, Hanyan Yang, Yaosheng Liu, Ruomei Wang, Bin Zhang, Guanlei Wang   +8 more
doaj   +1 more source

Dynamics of mitochondrial Ca2+ uptake in MICU1-knockdown cells [PDF]

, 2010
MICU1 (Ca2+ uptake protein 1, mitochondrial) is an important regulator of the MCU (Ca2+ uniporter protein, mitochondrial) that has been shown recently to act as a gatekeeper of the MCU at low [Ca2+]c (cytosolic [Ca2+]).
Montero, Mayte, Moreno Díaz-Calderón, Alfredo, Domínguez Lobatón, María Carmen, Fuente, Sergio de la, Fonteriz, Rosalba I., Fuente Pérez, Sergio De La, Álvarez Martín, Javier, Álvarez, Javier, Montenegro, Pablo, Matesanz Isabel, Jessica, Montero Zoccola, María Teresa, Fonteriz García, Rosalba Inés, Matesanz-Isabel, Jessica, Lobatón, Carmen D., Sergio de la Fuente, Pablo Montenegro, Carmen D. Lobatón, Rosalba I. Fonteriz, Alfredo Moreno, Mayte Montero, Moreno, Alfredo, Javier Alvarez   +21 more
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