Results 41 to 50 of about 567,581 (297)
Ca2+ Regulation in the Na+/Ca2+ Exchanger Involves Two Markedly Different Ca2+ Sensors [PDF]
Molecular Cell, 2006 The plasma membrane Na+/Ca2+ exchanger (NCX) is almost certainly the major Ca2+ extrusion mechanism in cardiac myocytes. Binding of Na+ and Ca2+ ions to its large cytosolic loop regulates ion transport of the exchanger. We determined the solution structures of two Ca2+ binding domains (CBD1 and CBD2) that, together with an alpha-catenin-like domain ...
Hilge, M, Aelen, J, Vuister, GW
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Evidence for the role of sound on the growth and signal response in duckweed
Plant Signaling & Behavior, 2023 Sound vibration, an external mechanical force, has been proven to modulate plant growth and development like rain, wind, and vibration. However, the role of sound on plants, especially on signal response, has been usually neglected in research.
Zi Ye +10 more
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Dynamics of mitochondrial Ca2+ uptake in MICU1-knockdown cells [PDF]
, 2014 MICU1 (Ca2+ uptake protein 1, mitochondrial) is an important regulator of the MCU (Ca2+ uniporter protein, mitochondrial) that has been shown recently to act as a gatekeeper of the MCU at low [Ca2+]c (cytosolic [Ca2+]).
Montero, Mayte +12 more
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Chinese Journal of Physiology, 2021 Ca2+-sensing receptors (CaSR), activated by elevated concentrations of extracellular Ca2+, have been known to regulate functions of thyroid cells, neurons, and endothelial cells (EC). In this report, we studied CaSR-mediated Ca2+ influx in mouse cerebral
Iat-Lon Leong +6 more
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ER localized bestrophin1 activates Ca2+ dependent ion channels TMEM16A and SK4
, 2009 Bestrophins form Ca2+ activated Cl- channels and regulate intercellular Ca2+ signaling1. We demonstrate that bestrophin 1 is localized in the endoplasmic reticulum (ER), where it physically interacts with stromal interacting molecule 1 (Stim1), the ER ...
Rainer Schreiber +13 more
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Cardiac Ca2+ Signaling and Ca2+ Sensitizers
Circulation Journal, 2008 The role of Ca2+ in cardiac excitation-contraction (E-C) coupling has been established by simultaneous measurements of contractility and Ca2+ transients by means of aequorin in intact myocardium and Ca2+ sensitive fluorescent dyes in single myocytes. The E-C coupling process can be classified into 3 processes: upstream (Ca2+ mobilization), central (Ca2+
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Role of Ca2+ signaling in skeletal muscle hypertrophy and atrophy
Journal of Physical Fitness and Sports Medicine, 2015 Skeletal muscle maintains an adequate volume that is commensurate with its surrounding environment. Although intracellular signaling molecules and pathways underlying the regulation of protein synthesis/degradation and subsequent muscle hypertrophy ...
Naoki Ito, Shin’ichi Takeda
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Decavanadate displaces inositol 1,4,5-trisphosphate (IP3) from its receptor and inhibits IP3 induced Ca2+ release in permeabilized pancreatic acinar cells [PDF]
, 1991 Inositol 1,4,5-trisphosphate (IP3) induced Ca2+ release in digitonin permeabilized rat pancreatic acinar cells is specifically inhibited by decavanadate.
M. Gratzl +9 more
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Effects of Storage Time on Electrolyte Content and pH Value in Rat Serum Samples
Shiyan dongwu yu bijiao yixue, 2022 Objective To observe the effects of serum sample placement time on the detection results of K +, Na+, Ca2+, Cl - and pH in sera of SD rats. MethodsThe sera of 20 male and 20 female SD rats were separated after blood collection from abdominal vein.
FENG Dingshan +5 more
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Ca2+ Heterogeneity Within a Ca2+ Spark [PDF]
Biophysical Journal, 2012 The Ca2+ spark is the elemental Ca2+ release event in excitation-contraction coupling. The synchronized summation of thousands (10,000 to 20,000 per cell) of these local Ca2+ release events will give rise to the normal Ca2+ transient that underlies contraction.
Brochet, Didier X.P. +1 more
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