CA 125: The past and the Future
The International Journal of Biological Markers, 1998 Over the last 15 years, substantial progress has been made in understanding the potential and the limitations of the CA 125 assay. More than 2000 papers have been published concerning laboratory and clinical studies of CA 125.
R.C. Bast +5 more
doaj +1 more source
Peripheral CA 125 levels in patients with uterine fibroids [PDF]
, 2017 CA 125, a marker of ovarian cancer, is also increased in otherwise normal women suffering from, for example, pelvic inflammatory disease, endometriosis and adenomyosis.
Bischof, P. +4 more
core
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Hubungan Tumor Marker Ca-125 Dengan Sifat Dan Tipe Sel Tumor Ovarium Di RSUD Arifin Achmad Pekanbaru [PDF]
, 2014 Ovarian tumor caused by inflammation or proliferation of ovarian's ephitelial, germinal, stroma cell and it can be benign and Malignant. Ovarian tumor had many tumor markers, the most known is Cancer Antigen 125 (CA-125).
Fatmawati, F. (Fatmawati) +2 more
core
TIMP-1 and VEGF-165 serum concentration during first-line therapy of ovarian cancer patients [PDF]
, 2010 Background Angiogenesis appears to play an important role in ovarian cancer. Vascular endothelial growth factor (VEGF) has recently been implicated as a therapeutic target in ovarian cancer.
Sven Mahner +63 more
core +1 more source
Nonconventional Ca(OH) 2 treatment of bamboo for the reinforcement of cement composites [PDF]
, 2020 This study compares the structural and morphological changes in Guadua angustifolia Kunth (GAK) fiber prepared in three different ways (chips, barkless and crushed) when non-conventional alkaline treatment is applied.
Ganjian, Esmaiel +2 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Boninite and Harzburgite from Leg 125 (Bonin-Mariana Forearc): A Case Study of Magma Genesis during the Initial Stages of Subduction [PDF]
, 1992 Holes drilled into the volcanic and ultrabasic basement of the Izu-Ogasawara and Mariana forearc terranes during Leg 125 provide data on some of the earliest lithosphere created after the start of Eocene subduction in the Western Pacific.
Arculus, Richard J. +6 more
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
CA‐125 variation in acute heart failure: a single‐centre analysis
ESC Heart Failure, 2022 Aims A decrease in carbohydrate antigen 125 (CA‐125) predicts survival advantage in chronic heart failure (HF); the impact of its variation in acute HF is unknown. We studied the association of CA‐125 decrease with prognosis in acute HF.
Patrícia Lourenço +6 more
doaj +1 more source