Results 71 to 80 of about 26,342,767 (265)

Treatment of Ruptured Ovarian Endometrioma with Extremely High CA 125, Moderately High CA 19-9 and CA 15-3 Level

open access: yes, 2013
In this case report, a ruptured ovarian endometrioma with a very high CA-125 level, moderately elevated CA 19-9, and CA 15-3 levels is presented.
Duran, Muzeyyen   +4 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Discovery of a Sinusoidal Pattern in the Cancer Antigen 15-3 Time Series of a Patient with Metastatic Breast Cancer

open access: yesApplied Medical Informatics
Cancer Antigen 15-3 (CA 15-3) is a glycoprotein commonly linked to breast cancer. Monitoring CA 15-3 levels is crucial for tracking disease progression and evaluating treatment response in patients with metastatic breast cancer. Although fluctuations in
Alexandros CLOUVAS
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Evaluation of CEA, TPA, CA 15-3, CA 549 and TPS in the monitoring of metastatic breast cancer

open access: yes, 1993
Monitoring the response to treatment in relapsed breast cancer patients is one of the chief uses of tumor markers. Thus far the carcinoembryonic antigen (CEA)-tissue polypeptide antigen (TPA)-breast cancer associated antigen 115 D8/DF3 (CA 15-3 ...
Nicolini A   +2 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Programma del concerto a Ca\u27 Foscari per la 26. riunione della SIPS. Ca\u27 Foscari, 15 settembre 1937

open access: yes, 1937
Programma del concerto di musica da camera eseguito, la sera del 15 settembre 1937, dal quartetto Poltronieri (Alberto Poltronieri - 1. violino, Ercole Giaccone - 2.
A, A
core  

Exploring the Significance of Cluster Analysis on Time-Series Measurement of Plasma Cancer Antigen 15-3 in a Patient with Metastatic Breast Cancer

open access: yesApplied Medical Informatics
Cancer Antigen 15-3 (CA 15-3) is a glycoprotein often linked to breast cancer. Elevated levels of CA 15-3, above the normal reference range of 30 U/mL (units per milliliter), are frequently found in the blood of patients with metastatic breast cancer ...
Alexandros CLOUVAS
doaj  

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

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