Results 71 to 80 of about 2,916,761 (236)

Serum miR-16 and CA15.3 combination as early diagnostic biomarkers for breast cancer in Egyptian females [PDF]

open access: yesEgyptian Journal of Pure and Applied Science
Background: Breast cancer (BC) represents one of the most lethal malignancies among women worldwide. MiRNAs play an important role in breast cancer diagnosis and progression. Inconsistent data about the expression level of miR-16 was reported in BC, thus
Sara Kamal   +3 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

CA 15-3, CRP, and LDH correlates with prognostic parameters in canine mammary neoplasms. [PDF]

open access: yesAnim Reprod, 2023
Pinheiro BQ   +5 more
europepmc   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Serum NSE, CEA, CT, CA 15-3 Levels in Human Lung Cancer

open access: yesThe International Journal of Biological Markers, 1990
The significance of neuron specific enolase (NSE) was investigated in comparison with other tumor markers (CEA, CT, CA 15-3) used in the diagnosis and treatment monitoring of lung cancer.
S. Nutini   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Time Series measurements of White Blood Cells (WBC) and plasma Cancer Antigen 15-3 (CA 15-3) in a patient with metastatic breast cancer, serving as a reference for assessing the clinical relevance of different clustering algorithms.

open access: yesApplied Medical Informatics
Clustering is highly valuable for analyzing cancer marker time series data. In a recent study, the significance of the K-means clustering algorithm was examined for the first time in evaluating time-series measurements of plasma Cancer Antigen 15-3 (CA ...
Alexandros CLOUVAS
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Prognostic Significance of CRP and CA 15-3 Levels in the Diagnosis of Breast Cancer: A Comparative Study

open access: yesRussian Open Medical Journal
Background — C-reactive protein (CRP) and cancer antigen 15-3 (CA 15-3) are commonly studied biomarkers in breast cancer, but their prognostic significance at diagnosis remains unclear. Aim: Our study aimed to assess the prognostic value of serum CRP and
Zein Al-Abideen Douba, Rama Ibrahim
doaj   +1 more source

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