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CA 15-3 Serum Levels in Ovarian Cancer
Oncology, 2009Serum levels of CA 15-3, an antigen expressed by human breast carcinoma cells, were measured in 58 ovarian cancer patients, 24 patients with benign ovarian tumor and 62 patients with benign gynecological conditions. Abnormally high serum CA 15-3 levels were found in 41 of 58 patients (71 %) with ovarian cancer.
Scambia S +6 more
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Analytical requirements and standardization of CA 15—3
Scandinavian Journal of Clinical and Laboratory Investigation, 1995The CA 15-3 assay could play, probably in combination with cytokeratin markers, a role in the detection of early recurrence and in monitoring therapy in metastatic breast cancer patients. The CA 15-3 assay is, however, not useful for early detection of breast cancer and has no prognostic significance.
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Breast cancer and clinical utility of CA 15—3 and CEA
Scandinavian Journal of Clinical and Laboratory Investigation, 1995This manuscript summarizes the experiences with CA 15-3 and CEA obtained in 8,000 breast cancer patients. These markers were usually in normal range (CEA < 6 micrograms/L, CA 15-3 < 40 U/L) before surgery and increased only before the development of distant metastases. 80% of all patients with metastases had elevated marker levels several months before
W, Jäger +3 more
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Ca 15-3 a Marker for the Megaloblastic Anaemia?.
Blood, 2005Abstract Ca 15-3 is a glycoprotein present in the cells of the mammary carcinoma and in some epithelial cells. Is a marker used for the monitoring of the breast and gastrointestinal carcinoma. The megaloblastic anaemia is an anaemia characterized by deficit of absorption of Vitamin B12 and is associated with gastritis atrophic and the ...
Vincenzo Mettivier +5 more
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The significance of determining CA 15-3 in the cytosol of breast cancer
Journal of Cancer Research and Clinical Oncology, 1992The identification of tumor markers in patients who had undergone operation for breast cancer provides important information in the follow-up in addition to evaluation by clinical and visual methods. The aim of our study was to determine the clinical prospective value of CA 15-3, mucin-like carcinoma-associated antigen and carcinoembryonic antigen in ...
K, Kosian +3 more
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CA 15-3 in patients with locoregional and metastatic breast carcinoma
Cancer, 1992The value of circulating CA 15-3 levels was assessed in 129 patients with recurrent breast carcinoma.Patients were divided into four subgroups, according to the following: Group A, locoregional recurrence alone; Group B, locoregional and subsequent systemic recurrence; Group C, combined locoregional and systemic recurrence; and Group D, differing sites
J G, Geraghty +4 more
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Clinical Applications of CA 15–3
1992Circulating breast cancer associated tumor markers have several potential clinical uses. Although many circulating molecules have been investigated as putative breast cancer markers, only a few have been found to have sufficient sensitivity and specificity to be useful clinically. Of these, carcinoembryonic antigen (CEA) has been the most commonly used
Daniel F. Hayes +2 more
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CEA and CA 15‐3 in primary and recurrent breast cancer
World Journal of Surgery, 1990AbstractTo evaluate CA 15‐3, a new breast cancer associated antigen, and to compare it with carcinoembryonic antigen (CEA), all patients presenting with breast cancer had preoperative and serial (3‐monthly) postoperative levels measured. Of 124 patients with primary breast cancer, 23% had an elevated CA 15‐3 (>25 units/ml) while 11% had an elevated ...
P J, O'Dwyer +5 more
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Informations Réactifs : CA 15-3
Immuno-analyse & Biologie Spécialisée, 2001Resume Cette rubrique est alimentee par les informations recueillies aupres de l'Agence francaise de securite sanitaire des produits de sante (direction de l'evaluation des dispositifs in vitro, departement diagnostic in vitro, unite enregistrement des reactifs) et des industriels.
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CA 15-3: Uses and limitation as a biomarker for breast cancer
Clinica Chimica Acta, 2010CA 15-3 which detects soluble forms of MUC-1 protein is the most widely used serum marker in patients with breast cancer. Its main use is for monitoring therapy in patients with metastatic disease. In monitoring therapy in this setting, CA 15-3 should not be used alone but measured in conjunction with diagnostic imaging, clinical history and physical ...
Michael J, Duffy +2 more
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