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Clinical Applications of CA 15–3
1992Circulating breast cancer associated tumor markers have several potential clinical uses. Although many circulating molecules have been investigated as putative breast cancer markers, only a few have been found to have sufficient sensitivity and specificity to be useful clinically. Of these, carcinoembryonic antigen (CEA) has been the most commonly used
Daniel F. Hayes +2 more
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Analytical requirements and standardization of CA 15—3
Scandinavian Journal of Clinical and Laboratory Investigation, 1995The CA 15-3 assay could play, probably in combination with cytokeratin markers, a role in the detection of early recurrence and in monitoring therapy in metastatic breast cancer patients. The CA 15-3 assay is, however, not useful for early detection of breast cancer and has no prognostic significance.
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CSF CA 15-3 in breast cancer-related leptomeningeal metastases
Journal of Neuro-Oncology, 2014The sensitivity of CSF cytology, the standard method for diagnosis of leptomeningeal metastases (LM), is low. Serum cancer antigen 15-3 (CA 15-3) is frequently used for the monitoring of patients with breast cancer (BC) and is a laboratory test available in most centers.
Emilie, Le Rhun +12 more
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CA 15-3 as a tumor marker in gynecological malignancies
Gynecologic Oncology, 1988Serum levels of CA 15-3 were measured in 778 samples from 270 patients with benign and malignant gynecological conditions. Malignant tumors were present in 180 patients including 58 cases with cancer of the ovary, 47 of the endometrium, 61 of the cervix, and 14 of the vulva.
G. Scambia +5 more
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[Evaluation of CA 15-3 radioimmunoassay].
Gan to kagaku ryoho. Cancer & chemotherapy, 1987The CA 15-3 RIA kit (Centocor Co.) based on a solid-phase radioimmunoassay was evaluated both experimentally and clinically. The results of a basic study of the reproducibility, recovery and dilution were very satisfactory. Serum levels of CA 15-3 were determined in 211 patients with malignancies including 13 breast cancers, 81 patients with benign ...
Y, Takemori +9 more
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La Revue de medecine interne, 1995
The precise clinical value of CA 15-3 antigen has yet to be determined. With no role in screening for early breast cancer and, even if CA 15-3 seems to be correlated with bulky initial tumor burden, it appears to have no independent prognostic value. The clinical interest of CA 15-3 remains the early detection of the first recurrence.
E, Antoine, L, Kayitalire, M, Spielmann
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The precise clinical value of CA 15-3 antigen has yet to be determined. With no role in screening for early breast cancer and, even if CA 15-3 seems to be correlated with bulky initial tumor burden, it appears to have no independent prognostic value. The clinical interest of CA 15-3 remains the early detection of the first recurrence.
E, Antoine, L, Kayitalire, M, Spielmann
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1995
CA 15-3 is a 290 000 Da cell surface antigen defined by a heterologous monoclonal antibody system employing two distinct antibodies. The first antibody — 115D8 — is specific for a human milkfat globule membrane antigen, whilst the second — DF3 — was derived by immunization with a membrane enriched fraction from human breast carcinoma.
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CA 15-3 is a 290 000 Da cell surface antigen defined by a heterologous monoclonal antibody system employing two distinct antibodies. The first antibody — 115D8 — is specific for a human milkfat globule membrane antigen, whilst the second — DF3 — was derived by immunization with a membrane enriched fraction from human breast carcinoma.
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Chemotherapy-induced pneumonitis associated with transient CA 15-3 elevation
Journal of Oncology Pharmacy Practice, 2020Introduction Development of hypersensitivity pneumonitis has been reported in association with combination chemotherapy consisting of gemcitabine and paclitaxel. However, diagnosis of this condition is based on computed tomography imaging and correlative bronchoalveolar findings on bronchoscopy.
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Talanta: The International Journal of Pure and Applied Analytical Chemistry, 2022
A. E. F. Oliveira +2 more
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A. E. F. Oliveira +2 more
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