Results 91 to 100 of about 26,349,951 (265)
Mìžnarodnij Endokrinologìčnij ŽurnalBackground. Breast cancer is a heterogenous malignancy and is one of the leading causes of cancer-related mortality in women worldwide. Recurrence as a barrier to long-term survivorship and effective patient management is a formidable challenge.
Muntaha Maddah Al Alouci +3 more
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Serum miR-16 and CA15.3 combination as early diagnostic biomarkers for breast cancer in Egyptian females [PDF]
Egyptian Journal of Pure and Applied ScienceBackground: Breast cancer (BC) represents one of the most lethal malignancies among women worldwide. MiRNAs play an important role in breast cancer diagnosis and progression. Inconsistent data about the expression level of miR-16 was reported in BC, thus
Sara Kamal +3 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Preoperative CA 15-3 and CEA serum levels as predictor for breast cancer outcomes [PDF]
, 2008 BACKGROUND: To investigate the association between tumor markers [cancer antigen 15-3 (CA 15-3) and carcinoembryonic antigen (CEA)] and clinicopathological parameters and patient outcomes in breast cancer.
김주희 +3 more
core +1 more source
Serum NSE, CEA, CT, CA 15-3 Levels in Human Lung Cancer
The International Journal of Biological Markers, 1990 The significance of neuron specific enolase (NSE) was investigated in comparison with other tumor markers (CEA, CT, CA 15-3) used in the diagnosis and treatment monitoring of lung cancer.
S. Nutini +4 more
doaj +1 more source
CA 15-3, CRP, and LDH correlates with prognostic parameters in canine mammary neoplasms. [PDF]
Anim Reprod, 2023 Pinheiro BQ +5 more
europepmc +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Applied Medical InformaticsClustering is highly valuable for analyzing cancer marker time series data. In a recent study, the significance of the K-means clustering algorithm was examined for the first time in evaluating time-series measurements of plasma Cancer Antigen 15-3 (CA ...
Alexandros CLOUVAS
doaj
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source