Results 101 to 110 of about 124,349,391 (271)

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

FEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim, Thi Thanh Mai Tran, Nakyung Kang, Min‐Woo Lee, Mihye Lee   +4 more
wiley   +1 more source

Prognostic Significance of CRP and CA 15-3 Levels in the Diagnosis of Breast Cancer: A Comparative Study

Russian Open Medical Journal
Background — C-reactive protein (CRP) and cancer antigen 15-3 (CA 15-3) are commonly studied biomarkers in breast cancer, but their prognostic significance at diagnosis remains unclear. Aim: Our study aimed to assess the prognostic value of serum CRP and
Zein Al-Abideen Douba, Rama Ibrahim
doaj   +1 more source

Diagnostic impact of CEA and CA 15-3 on chemotherapy monitoring of breast cancer patients. [PDF]

J Circ Biomark, 2022
Hasan D.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Association between CA 15‑3 and progression of interstitial lung disease in a case of coexisting systemic sclerosis and recurrent breast cancer: A case report. [PDF]

Mol Clin Oncol, 2022
Ohara M, Koi Y, Sasada T, Kajitani K, Mizuno S, Takata A, Okamoto A, Nagata I, Sumita M, Imachi K, Watanabe M, Daimaru Y, Yoshida Y.   +12 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

[Tumor markers in the early diagnosis of recurrence in gynecologic neoplasms: combined determination of CA-125, CA 15-3, CA 72.4, SCC, 90 K]

, 1991
In 156 patients with gynecologic neoplasia the sieric levels of tumor markers (CA 125, CA 15-3, CA 72.4, SCC and 90 K) before the primary treatment and during the follow-up have been evaluated.
Romanini, C., Tranquilli, A. L, Pallotta, M. R, Arduini, D, Garzetti, G. C, Di Lauro, R. M, Valensise, H, CIAVATTINI, Andrea, MARCHEGIANI, Francesca   +8 more
core  

Novel sensor for the determination of CA 15-3 in serum of breast cancer patients based on Fe-gallic acid complex doped in modified cellulose polymer thin films. [PDF]

RSC Adv, 2023
AlGhamdi HA, AlZahrani YM, Alharthi S, Mohy-Eldin MS, Mohamed EH, Mahmoud SA, Attia MS.   +6 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Point Pinos, California, ca. 1850 [picture].

In: Watercolours of a voyage around South America to the Society Islands and Hawaii, ca.1850.; Rex Nan Kivell Collection NK2602/15.; Title from inscription lower ...

core