A combinatorial CAAR-T cell strategy to eliminate factor VIII inhibitors in preclinical models of hemophilia A [PDF]
iScienceSummary: Chimeric autoantibody receptor T (CAAR-T) cell therapy extends CAR-T technology to target autoreactive immune cells, offering a novel approach for treating autoimmune disorders.
Wenjie Li +7 more
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Chimeric autoantibody receptor T cells specifically eliminate Graves’ Disease autoreactive B cells [PDF]
Frontiers in ImmunologyIntroductionChimeric antigen receptor (CAR) T cells have recently become an important treatment for hematological cancers by efficiently eliminating B cells.
Abigail Cheever +6 more
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Chimeric Autoantibody Receptor- and/or Peptide-MHC-Based CAR Therapies for Targeted Elimination of Antigen-Specific B or T Cells in Hypersensitivity Disorders Such as Allergies and Autoimmune Diseases [PDF]
CellsHypersensitivity reactions are dysregulated and potentially devastating immune responses, characterized by a tendency to become chronic. They target either self-proteins or harmless foreign proteins and are driven by both T and B cells. Although numerous
Isidora Protić-Rosić +4 more
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CAR-T therapy: pioneering a new era in the treatment of autoimmune diseases [PDF]
Frontiers in ImmunologyCAR-T therapy, an innovative immunotherapeutic approach, genetically modifies T cells to express CARs, enabling targeted destruction of specific antigen-expressing cells.
Yuanhao Wu +7 more
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Advance in chimeric antigen receptor T therapy in autoimmune diseases [PDF]
Frontiers in ImmunologyAutoimmune diseases are a group of diseases in which the body’s immune system misrecognizes its own antigens resulting in an abnormal immune response, which can lead to pathological damage to or abnormal functioning of its own tissues. Current treatments
Xiaolan Ji +4 more
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Jurnal Siasat Bisnis, 2021 The purpose of this research is to examine the effect of SRI index on abnormal return of added to and deleted stocks of two countries, Indonesia (SRI-KEHATI) and Malaysia (FTSE4GBM).
Klara Petra Theodora Targanski +1 more
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Is the prevalence of risk factors, clinical presentations and severity of coronary artery diseases (CAD) in patients with very early and premature CAD are different from mature CAD patients?: A registry- based cross-sectional study [PDF]
Global EpidemiologyIntroduction: The present study aims to compare the risk factors, clinical presentation, and severity of coronary artery involvement in young compared to elderly CAD patients to assess the cardiovascular health status for better disease management and ...
Mohammad Haji Aghajani +5 more
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Heliyon, 2023 Background: Recent evidence suggests that B cells and autoantibodies have a substantial role in the pathogenesis of Multiple sclerosis. T cells could be engineered to express chimeric autoantibody receptors (CAARs), which have an epitope of autoantigens ...
Maryam Sahlolbei +10 more
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A rule-based theoretical account of social stories to address the double empathy problem
Frontiers in Psychology, 2023 Social Stories™ (SS) is one of the most popular and researched interventions for autistic children. To date, research that focuses on outcomes has been prioritized over the investigation of the psychological mechanisms that inform the intervention.
Louis John Camilleri +3 more
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Cumhuriyet Üniversitesi İktisadi ve İdari Bilimler Dergisi, 2022 Bu çalışmada STOXX Avrupa Futbol Endeksinde işlem gören 14 futbol kulübünün transfer (satın alma) duyurularına yatırımcıların (futbol kulüplerinin hisse senedi için) tepkisi analiz edilmiştir.
Binali Selman Eren
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