Results 51 to 60 of about 4,624,700 (323)

A Single-Actuated, Cable-Driven, and Self-Contained Robotic Hand Designed for Adaptive Grasps

open access: yesRobotics, 2021
Developing a dexterous robotic hand that mimics natural human hand movements is challenging due to complicated hand anatomy. Such a practical design should address several requirements, which are often conflicting and force the designer to prioritize the
Negin Nikafrooz, Alexander Leonessa
doaj   +1 more source

A new hand rehabilitation system based on the cable-driven mechanism and dielectric elastomer actuator [PDF]

open access: yesMechanical Sciences, 2020
The increasing number of patients with hand disabilities after strokes or peripheral nerve injuries necessitates the continuous development of rehabilitation system devices to accelerate muscle recovery and to help patients regain the motor functions of ...
H. Amin   +4 more
doaj   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Modeling and Verification of Cable-Hole Transmission Tension Ratio Considering the Cable Lateral Extrusion

open access: yesMachines
Cable-hole transmission is widely applied in cable-driven mechanisms to reduce the mechanical size. However, the driving tension is attenuated with the cable threading through the hole caused by uncertain factors such as local deformation, friction, and ...
Haiyu Gu   +4 more
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

A planar parallel 3-DOF cable-driven haptic interface [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2009
In this paper, a cable-driven planar parallel haptic interface is pre- sented. First, the velocity equations are derived and the forces in the cables are obtained by the principle of virtual work.
Clément Gosselin   +2 more
doaj  

Multi-Joint Bionic Mechanism Based on Non-Circular Gear Drive

open access: yesBiomimetics, 2023
Aiming at the nonlinear expansion/contraction drive problem between different cables in multi-joint cable drive mechanisms, a mechanical drive method based on a non-circular gear drive was proposed, which could replace the servo-sensing control system ...
Dawei Liu, Tao Zhang, Yuetong Cao
doaj   +1 more source

Stiffness Analysis and Measurement Method for a 3-DOF Cable-Driven Joint Module

open access: yes, 2016
A modular cable-driven manipulator that consists of a number of cable-driven joint modules can produce intrinsically-safe motions due to its light-weight structure.
Kaisheng Yang   +3 more
core   +1 more source

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