Results 51 to 60 of about 1,847,469 (309)
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Machines, 2023 The separation of gangues from coals with robots is an effective and practicable means. Therefore, a cable-suspended gangue-sorting robot (CSGSR) with an end-grab was developed in our early work.
Peng Liu +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Uniform-tension form-finding design for asymmetric cable-mesh deployable reflector antennas
Advances in Mechanical Engineering, 2016 Space antennas with high gain and high directivity are in great demand for future communication and observation applications. Deployable cable-mesh reflector antennas are required to be tensioned in a self-equilibrated state through form-finding design ...
Guigeng Yang +3 more
doaj +1 more source
Mechanical Engineering Journal, 2015 This study investigates the robustness of a space reflector structure consisting of radial ribs and hoop cables by using the multiobjective optimization method.
Ryo KODAMA +3 more
doaj +1 more source
Variational Mode Decomposition Based Time-Varying Force Identification of Stay Cables
Applied Sciences, 2021 Stay cables are important structural members of cable-stayed bridges, which play a significant role in the health monitoring and assessment of cable-stayed bridges.
Shitong Hou +6 more
doaj +1 more source
, 2023 Magnetic flux sensors are commonly used in monitoring the cable force, but the application of the sensors in large diameter non-closed Galfan cables, as those adopted in Yueqing Gymnasium which is located in Yueqing City, Zhejiang Province, China and is ...
Zhang, Hexin +3 more
core +1 more source
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Relaxation Behavior of Cerclage Cables and Its Effect on Bone Clamping Force
BioengineeringCerclage is an orthopedic surgical fixation technique using a cable wrapped, tensioned, and secured around a bone’s circumference. It is important to minimize the loss in cable tension that often occurs due to stress relaxation.
Audrey Moffat +5 more
doaj +1 more source
The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp +4 more
wiley +1 more source