Results 121 to 130 of about 56,978 (263)

Immunometabolic Modulation by Low‐Dose Sodium Butyrate: PI3K/Akt/mTOR Signalling Orchestrates Macrophage Polarization to Protect Against Clostridioides difficile Colitis

Immunology, EarlyView.
Clostridioides difficile toxins TcdA and TcdB enter intestinal epithelial cells (IECs) via specific receptors, disrupt tight‐junction integrity and activate PI3K/Akt/mTOR signalling, promoting inflammasome assembly and IL‐1β release. Toxin‐induced IEC apoptosis further weakens the epithelial barrier.
Sisi Zhang, Zhou Jingxiang, Caixia Tan, Yuanyuan Xiao, Ju Zou, Biyue Tian, Anhua Wu, Chunhui Li   +7 more
wiley   +1 more source

Ramucirumab induces apoptosis in Caco-2 cells via mitochondrial impairment and caspase activation. [PDF]

Saudi Pharm J
Al-Dogmi AM, Al-Anazi KM, Qamar W, Farah MA.   +3 more
europepmc   +1 more source

Periodontitis and Inflammatory Bowel Diseases: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review aims to provide a conceptual framework for understanding the mechanistic interplay between periodontitis and IBD, with a particular emphasis on the microbial and immunological crosstalk linking the oral cavity and the gastrointestinal tract.
Ana Paula V. Colombo, Adriana M. de Oliveira, Nobuhiko Kamada, Sho Kitamoto   +3 more
wiley   +1 more source

Mechanisms of Cell Uptake and Transport of Xanthophylls in the Caco-2 Cell Model. [PDF]

Nutrients
Wu F, Chen N, Peng Y, Li M, Ni Y, Li T, Liu R, Wen X.   +7 more
europepmc   +1 more source

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

Remineralisation of Reverse Osmosis (RO) Water Using Synthetic Aragonite

Water and Environment Journal, EarlyView.
ABSTRACT Reverse osmosis (RO) treated water often requires remineralisation to restore Ca2+ ions, hardness and alkalinity, particularly for potable water. This study compares the dissolution characteristics of two forms of calcium carbonate, aragonite and calcite.
Yuqing Wu, Marcus Yio, Ian Cranshaw, Christopher Cheeseman   +3 more
wiley   +1 more source

The effects of β-caryophyllene on butyrate utilization and metabolism in Caco-2 cells. [PDF]

Sci Rep
Scroggins H, Kent-Dennis C, May J, Harmon DL, Klotz JL.   +4 more
europepmc   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Evaluation of agmatine's anti-cancer efficacy in Caco-2 colorectal adenocarcinoma cells. [PDF]

Med Oncol
Tanoglu EG, Gokce MS, Karamese M, Altuntas S, Bayrak AM, Tanoglu A.   +5 more
europepmc   +1 more source

Caco-2 Cell Co-Culture Alters the Molecular Size of Igl1 and Its Extracellular Fragments in <i>Entamoeba histolytica</i>. [PDF]

Pathogens
Kato K, Kudo M, Unno H, Hatakeyama T, Tachibana H.   +4 more
europepmc   +1 more source