Results 141 to 150 of about 97,542,255 (296)

Interfacially Engineered Alginate/Hydroxyapatite Biocomposites With High Strength and Toughness

Polymer Composites, EarlyView.
Pre‐crosslinking alginate with Ca2+ prior to hydroxyapatite (HAP) formation reduces residual Ca2+ bridging and promotes stronger carboxylate‐hydroxyapatite interfacial interactions, yielding composites with markedly higher strength, stiffness, and toughness than those prepared by the opposite sequence.
Yui Okuda, Tadashi Mizutani, Eiichi Kido, Go Matsuba   +3 more
wiley   +1 more source

Evaluation of the Expression of Virulence Factors of V. cholerae After Interaction With the Human Colon Adenocarcinoma (Caco-2) Cell Line

Canadian Journal of Infectious Diseases and Medical Microbiology
Cholera remains a global challenge, and understanding how V. cholerae adapts to environmental condition is essential for innovating new management strategies. This research aims to examine the expression of ctxAB, tcpA, and hlyA genes in V.
Mohammadreza Kheradmand, Masoumeh Saberpour, Bita Bakhshi, Mahboube Bahroudi   +3 more
doaj   +1 more source

Plant responses to iron nutrition with emphasis on the underutilized crop tef (Eragrostis tef): A review

PLANTS, PEOPLE, PLANET, EarlyView.
Iron (Fe) deficiency limits the physical health, cognitive development, and economic output of billions of people globally, especially children and productive‐age women. Tef is an underutilized and stress‐resilient crop, which is becoming popular for its grains containing high bioavailable Fe and has the potential to mitigate Fe deficiency.
Muhammad Numan, David Remington, Ayalew Ligaba‐Osena   +2 more
wiley   +1 more source

Caco-2 Cell [PDF]

, 2020
openaire   +1 more source

Physiologically based pharmacokinetic modeling and simulation of topiramate in populations with renal and hepatic impairment and considerations for drug–drug interactions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 510-522, March 2025.
Abstract Topiramate (TPM) is a broad‐spectrum antiepileptic drug (AED) commonly prescribed for approved and off‐label uses. Routine monitoring is suggested for clinical usage of TPM in special population due to its broad side effect profile. Therefore, it is crucial to further explore its pharmacokinetic characteristics.
Shuqing Chen, Chaozhuang Shen, Yuchen Tian, Yuhe Peng, Jing Hu, Haitang Xie, Ping Yin   +6 more
wiley   +1 more source

Bioenhancer‐Driven Modulation of Membrane Dynamics Improves B‐Vitamin Uptake in Caco‐2 Cells

ChemFoodChem
Enhancing the bioavailability of B vitamins can increase their biological efficacy while reducing resource use in supplement production. Bioavailability can be improved through strategies such as microencapsulation, micellization, or the application of ...
Verena Preinfalk, Bernhard Blank‐Landeshammer, Marina Bishara, Sigrid Ihninger, Katja Essl, Stefanie Atzmüller, Mara Heckmann, Marcus Iken, Mario Brameshuber, Julian Weghuber   +9 more
doaj   +1 more source

Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.
Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo, Woojin Jung, Tham Thi Bui, Hwi‐yeol Yun, Jung‐woo Chae, Jeremiah D. Momper   +5 more
wiley   +1 more source

Binding of NoV VLPs to Caco-2 cells depended on the state of cell differentiation.

, 2013
Caco-2 cells were incubated with VLPs at 4°C and subjected to immunofluorescence microscopy (A). Areas of VLP binding on undifferentiated and differentiated Caco-2 cells were quantified with Adobe Photoshop software.
Chie Kurihara (422339), Tsukasa Matsuda (80758), Ryota Hokari (422344), Tomoichiro Oka (422340), Yoshiki Fujii (381796), Soichiro Miura (422345), Reiko Takai-Todaka (422342), Kazuhiko Katayama (239561), Takaji Wakita (109321), Kosuke Murakami (422338), YoungBin Park (422343), Takashi Shimoike (422341)   +11 more
core   +1 more source

Betulinic Acid Enema Alleviates Colitis by Targeting Vitamin D Receptor to Protect the Intestinal Mucosal Barrier and Modulate Mucosa‐Associated Microbiota

Phytotherapy Research, EarlyView.
ABSTRACT Ulcerative colitis (UC) is a chronic inflammatory disease of the colon with limited effectiveness and safety of current drug therapies. Betulinic acid (BA) is a naturally occurring pentacyclic triterpenoid present in traditional Chinese medicines used clinically as retention enemas for UC, but its direct effects and mechanisms remain unclear ...
Lina Dong, Yuanxia Gao, Qian Li, Guangxin Chen, Dong Yang, Liping Zhao, Xiaojing Liu, Shumei Lin   +7 more
wiley   +1 more source

Molecular Modeling-Based Delivery System Enhances Everolimus-Induced Apoptosis in Caco‑2 Cells

ACS Omega, 2019
Marwan Abdelmahmoud Abdelkarim Maki, Palanirajan Vijayaraj Kumar, Shiau-Chuen Cheah, Yeong Siew Wei, Mayasah Al-Nema, Omer Bayazeid, Abu Bakar Bin Abdul Majeed   +6 more
doaj   +1 more source