Results 161 to 170 of about 97,542,255 (296)

Hydrochem, an Integrated R Package for the Analysis and Visualization of Hydrochemical Data

Groundwater, EarlyView.
We present hydrochem, an open‐source R package that simplifies hydrochemical data analysis through reproducible workflows, automated calculations, and advanced visualization tools. It enables flexible and reliable interpretation of complex water chemistry datasets, supporting researchers and practitioners in groundwater quality assessment and resource ...
Guillaume Cinkus, Raphaël Bondu
wiley   +1 more source

Immunometabolic Modulation by Low‐Dose Sodium Butyrate: PI3K/Akt/mTOR Signalling Orchestrates Macrophage Polarization to Protect Against Clostridioides difficile Colitis

Immunology, EarlyView.
Clostridioides difficile toxins TcdA and TcdB enter intestinal epithelial cells (IECs) via specific receptors, disrupt tight‐junction integrity and activate PI3K/Akt/mTOR signalling, promoting inflammasome assembly and IL‐1β release. Toxin‐induced IEC apoptosis further weakens the epithelial barrier.
Sisi Zhang, Zhou Jingxiang, Caixia Tan, Yuanyuan Xiao, Ju Zou, Biyue Tian, Anhua Wu, Chunhui Li   +7 more
wiley   +1 more source

Periodontitis and Inflammatory Bowel Diseases: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review aims to provide a conceptual framework for understanding the mechanistic interplay between periodontitis and IBD, with a particular emphasis on the microbial and immunological crosstalk linking the oral cavity and the gastrointestinal tract.
Ana Paula V. Colombo, Adriana M. de Oliveira, Nobuhiko Kamada, Sho Kitamoto   +3 more
wiley   +1 more source

Effects of vitamins A and E on eprinomectin transport in Caco-2 cells. [PDF]

Vet Med (Praha)
Gunes Y, Gultekin Y, Dogan O, Anlas C, Ustuner O, Yilmaz N, Bakirel T.   +6 more
europepmc   +1 more source

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

An Insectified Caco-2 Cell-Based Assay to Monitor Pesticide Transport Processes and Pharmacokinetics. [PDF]

Int J Mol Sci
Skouloudaki K, Denecke S, Vogelsang K, Pergantis SA, Vontas J.   +4 more
europepmc   +1 more source

Remineralisation of Reverse Osmosis (RO) Water Using Synthetic Aragonite

Water and Environment Journal, EarlyView.
ABSTRACT Reverse osmosis (RO) treated water often requires remineralisation to restore Ca2+ ions, hardness and alkalinity, particularly for potable water. This study compares the dissolution characteristics of two forms of calcium carbonate, aragonite and calcite.
Yuqing Wu, Marcus Yio, Ian Cranshaw, Christopher Cheeseman   +3 more
wiley   +1 more source

Fructose Promotes Oxidative Stress, Sphingolipid Remodelling and Transient Intestinal Barrier Dysfunction in Differentiated Caco-2 Cells. [PDF]

Nutrients
Serreli G, Melis MP, Guerriero C, Manis C, Tolle G, Sanna G, Orrù G, Fais S, Caboni P, Deiana M.   +9 more
europepmc   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Uptake and Transport of Monotropein and Monotropein Esters in a Caco-2/HT29-MTX-E12 Co-Culture Model. [PDF]

Mol Nutr Food Res
Zielinski C, Schmalle V, Lauer LA, Hammerschick T, Rüttler F, Vetter W, Frank J, Jiménez-Aspee F.   +7 more
europepmc   +1 more source