Results 111 to 120 of about 346,942 (313)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Non-communicable airway disease and air pollution in three African Countries: Benin, Cameroon and The Gambia

IJTLD Open
BACKGROUND: Air pollution exposure can increase the risk of development and exacerbation of chronic airway disease (CAD). We set out to assess CAD patients in Benin, Cameroon and The Gambia and to compare their measured exposures to air pollution ...
B. Awokola, H. Lawin, O. Johnson, A. Humphrey, D. Nzogo, L. Zubar, G. Okello, S. Semple, E. Awokola, G. Amusa, N. Mohammed, C. Jewell, A. Erhart, K. Mortimer, G. Devereux, B.H. Mbatchou-Ngahane   +15 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Diagnostic Accuracy of MDCT Coronary Angiography in Patients with Ischemic Heart Disease

Journal of Pharmacy and Bioallied Sciences
Introduction: One of the main causes of illness and death in both India and globally is coronary artery disease, or CAD. Previously, the majority of conventional catheter examinations were performed simply for diagnostic purposes.
Arti Kumari, Suresh Kumar Toppo, Prakash Kumar, Rajeev Kumar Ranjan, Anima R. Xalxo, Nisha Rai, Harsha Kaur   +6 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

A CAD INTERFACE FOR PRODUCT CUSTOMIZATION

, 2010
Product customization has become more prevalent in today’s manufacturing industry. In fact, given a choice in today’s society and taking into consideration the present technology, customers would prefer a product that can be built according to their ...
Efendy, Eddy
core  

An occupational survey to determine the entry level CAD skills and competencies required by employers of civil engineering technicians in the Northeast Wisconsin Technical College district [PDF]

, 2000
Includes bibliographical references.The purpose of this study was to identify the CAD related technical skills and competencies that are required for employability at an entry-level position as a civil engineering technician. The majority of employers
Francisco, Gene R., G. Francisco
core  

PROJEKTMÓDSZER ALKALMAZÁSA A CAD-CAM KÉPZÉSBEN EGY ADOTT KOMPLEX MEGVALÓSÍTÁSON KERESZTÜL

, 2022
PROJEKTMÓDSZER ALKALMAZÁSA A CAD-CAM KÉPZÉSBEN EGY ADOTT KOMPLEX MEGVALÓSÍTÁSON KERESZTÜLegyetemiGépészmérnökAdminokkal és témavezetővel egyeztetve átkerült a megfelelő gyűjteménybe ...
Balogh, Ervin
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Geometry Compression for Collaborative CAD Applications

, 2022
S.121-129In this paper we discuss the requirements of common distributed CAD applications for an efficient and complete compression and decompression of 3D models.
Stork, A., Benölken, P.
core