Results 101 to 110 of about 346,942 (313)

Virtual Reality und Kooperation als integraler Bestandteil von CAD: Eine vereinheitlichte Systemarchitektur

, 2022
S.34-49In der Konstruktion, der Domaene von CAD-Systemen, kommen vermehrt auch Werkzeuge zum computerunterstuetzten kooperativen Arbeiten (CSCW-Tools) und Virtual Reality (VR) Systeme zum Einsatz.
Rix, J., Stork, A., Jasnoch, U.
core  

Long-term single antiplatelet therapy for patients with acute coronary syndrome at high-risk for ischemia and bleeding: a precision cohort study

Frontiers in Cardiovascular Medicine
BackgroundTo compare the prognostic effects of different single antiplatelet therapy (SAPT) regimens (aspirin vs. clopidogrel) in patients with acute coronary syndrome (ACS) at high-risk for ischemia and bleeding following percutaneous coronary ...
Ma Wanda, Ma Wanda, Lei Mengjie, Wang Jingyao, Sun Xue, Wang Xiao, Li Cairong, Li Yachao, Zhao Zhigang, Xue Zengming   +9 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Uma metodologia para integração CAD/CAPP/CAM voltada para manufatura remota de peças rotacionais baseada na internet [PDF]

, 2005
Tese [doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-graduação em Engenharia MecânicaEsta tese de doutorado apresenta uma metodologia para integração CAD/CAPP/CAM voltada para manufatura remota de peças ...
Alvares, Alberto Jose
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ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Uma abordagem para criação e compartilhamento de dados de peças através da integração CAD-RDBMS [PDF]

, 2001
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia MecânicaAs estratégia atuais de desenvolvimento de produtos compartilham um requisito fundamental: a necessidade de ferramentas ...
Silva Júnior, Alvino Cesário da
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Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

A hierarchical multilevel modeling framework for the creation of high-quality solid models in parametric feature-based CAD systems

[EN] Building on the premise that quality is a complex and multifaceted concept, we advocate for the structuring of the concept of quality in engineering design parametric CAD modeling by using three hierarchical levels. The goal is to successfully parse
Company, Pedro, Camba, Jorge D., Justel, Daniel, Company, P., Justel, D., Camba, J.D., Aranburu, A., Aranburu, Aritz, Contero, Manuel   +8 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Normungsaktivitäten in Graphik und CAD

, 2022
S.11-18Durch die Entwicklung von Referenzmodellen für graphische Systeme und CAD-Systeme soll eine Harmonisierung und Klassifizierung der graphischen Systeme ermöglicht werden.
Noll, S., Klement, K., Froböse, L., Poller, J., Burkert, A.   +4 more
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