Results 81 to 90 of about 346,942 (313)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Szakdolgozatomba az általam három legjobban ismert CAD rendszer bemutatását céloztam meg. Ezek az ArchiCAD, a FactoryCAD és a SolidWorks. A CAD fogalma, a CAD rendszerek kialakulásának történelme mellett álltalánosan a CAD rendszerek előnyeiről is szót ...
Böszörményi, Csaba
core
CAD models in collaborative environment - Hybrid modeling strategies
S.151-157Within the information-processing concepts in a collaboration environment, CAD technology has been assigned the role of an "engineering backbone".
Roth-Koch, S.
core
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Uma interface CAD/CAM para a programação fora de linha de robôs industriais / [PDF]
Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico.Este trabalho trata do problema do planejamento e programação de trajetórias em manipuladores servo controlados, com ênfase no uso das técnicas de projeto e de manufatura
Toledo, Leonardo Bastos de
core
Advanced quantum computers have the capability to perform practical quantum computing to address specific problems that are intractable for classical computers.
Jieyi Chen +6 more
doaj +1 more source
Type 2 diabetes (T2DM) is one of the key predictors of coronary artery disease (CAD) and its complications. Currently, along with metabolic risk factors for CAD, much attention has been given to the study candidate genes, including platelet fibrinogen ...
Elvira F. Muslimova +4 more
doaj +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source

