Results 121 to 130 of about 346,942 (313)

A data transformation method for CAD and GIS based on semantic and evolution theory(一种使用语义和遗传进化思想的CAD和GIS数据转换方法)

open access: yesZhejiang Daxue xuebao. Lixue ban, 2012
为提高CAD和GIS数据转换的效率和准确性,利用语义映射关系和生物种群进化的思想,设计了 一种用于数据转换的语义适配器,提出了一套实用、高效的数据转换模型.实例表明,该模型具有较好的实用价值,在一定程度上能够解决CAD和GIS数据智能转换的问题.
XUFang-bin(徐方斌)   +5 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Computergraphik für CAD - ein F&E-Beitrag aus Darmstadt

open access: yes, 2022
S.9-45In diesem Heft wird über einige der F und E Arbeiten aus Darmstadt berichtet, um einen Querschnitt zu dem Thema "CAD und Computergraphik" zu geben.
Rix, J., Encarnação, José L.
core  

Features of the pathogenesis, diagnosis and treatment of myocardial ischemia with non-obstructive coronary arteries

open access: yesЕвразийский Кардиологический Журнал
Among the most dangerous causes of mortality worldwide, coronary artery disease (CAD) remains the leading cause. Despite the fact that atherosclerosis of the coronary arteries is the main cause of the development of coronary artery disease, clinicians ...
E. A. Khachirova, M. D. Iarovoi
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Metric for Automated Detection and Identification of 3D CAD Elements in 3D Scanned Data [PDF]

open access: yes, 2007
Being able to efficiently compare as-built against as-planned 3D states is critical for performing efficient building and infrastructure construction, maintenance, and management.
Bosche, Frederic Nicolas, Haas, Carl
core  

Veränderung der Konstruktionsarbeit durch die CAD-NC-Integration

open access: yes, 2022
S.73-81Die CAD/NC-Integration, ein vorwiegend in CNC-Werkzeugmaschinenfertigungsbereichen mit hoher (Facharbeiter-)Qualifikation genutzter Integrationspfad des "Computer Integrated Manufacturing (CIM)" verändert die Arbeit der Konstrukteure und ...
Schneider, R.
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Adaptionsmöglichkeiten in modernen CAD-Systemen: Bewertung, Konzeption und Realisierung

open access: yes, 2022
S.343-356Die Qualitaet moderner Software und folglich deren Akzeptanz wird letztlich durch das Mass an Benutzbarkeit, das dem Anwender entgegengebracht wird, definiert. Dies gilt insbesondere fuer so komplexe Anwendungen wie CAD-Systeme und speziell fuer
Stork, A., Encarnacao, L.M.
core  

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