Results 101 to 110 of about 12,771,392 (254)

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Normungsaktivitäten in Graphik und CAD

open access: yes, 2022
S.11-18Durch die Entwicklung von Referenzmodellen für graphische Systeme und CAD-Systeme soll eine Harmonisierung und Klassifizierung der graphischen Systeme ermöglicht werden.
Noll, S.   +4 more
core   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Tecnologia CAD/CAM [PDF]

open access: yes, 2013
TCC (graduação) – Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Odontologia.Nas últimas décadas, ocorreu um rápido avanço da ciência e um grande desenvolvimento tecnológico em diversas áreas.
Petter, Odara Íris
core  

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

A CAD INTERFACE FOR PRODUCT CUSTOMIZATION [PDF]

open access: yes, 2010
Product customization has become more prevalent in today’s manufacturing industry. In fact, given a choice in today’s society and taking into consideration the present technology, customers would prefer a product that can be built according to their ...
Efendy, Eddy
core  

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

CAD '92. Neue Konzepte zur Realisierung anwendungsorientierter CAD-Systeme. GI-Fachtagung

open access: yes, 2022
Die Tagung CAD'92 war die erste Fachtagung der Gesellschaft für Informatik zum Thema "Rechnertinterstütztes Entwerfen und Konstruieren". Schwerpunkte der Tagung waren neue Konzepte zur Realisierung anwendungsorientierter CAD-Systeme.

core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

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