Results 91 to 100 of about 12,242,462 (299)
Capturing and analysing how designers use CAD software [PDF]
Current Computer-Aided Design (CAD) packages support the storage of the final design models and solutions in different formats, and PLM software manages the high-level information about the design process, such as the versioning of the design solutions ...
PERNOT, Jean-Philippe +3 more
core
Background: Patients with coronary artery disease (CAD) had significantly lower bile acid excretion (BAE) compared with non-CAD patients, leading to the hypothesis that the inability to efficiently excrete bile acids leads to coronary atherosclerosis ...
Gideon Charach +5 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
A CAD INTERFACE FOR PRODUCT CUSTOMIZATION [PDF]
Product customization has become more prevalent in today’s manufacturing industry. In fact, given a choice in today’s society and taking into consideration the present technology, customers would prefer a product that can be built according to their ...
Efendy, Eddy
core +1 more source
THE USE OF CAD METHODS FOR DESIGNING BLOWOUT PREVENTERS BOP IN OIL INDUSTRY [PDF]
Best practice design and analysis of operational safety requires CAD modeling of these BOP.The primary objective for this paper was to design and select a suitable BOP system to meet the applications and proposing CAD solutions to improve the operation
Marius STAN
doaj
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Novel network biomarkers profile based coronary artery disease risk stratification in Asian Indians
Background: Multi-marker approaches for risk prediction in coronary artery disease (CAD) have been inconsistent due to biased selection of specific know biomarkers.
Rajani Kanth Vangala +4 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source

