Results 191 to 200 of about 383,770 (381)

Novel Vascularized Human Liver Organoids for Modeling Alcohol‐Induced Liver Injury and Developing Hepatoprotective Therapy

Advanced Science, EarlyView.
This study successfully engineered vascularized liver organoids (3HLOs) by co‐culturing human reprogrammed hepatocyte‐like cells (hrHLs) with human umbilical vein endothelial cells (HUVECs) and human umbilical mesenchymal stem cells (HUMSCs). Upon implantation, the 3HLOs established functional vascular anastomosis with the host circulation and ...
Kangdi Yang, Xiayan Chu, Xuerui Wang, Wenkun Zhang, Jinnuo Lu, Chuting Xu, Shoucheng Hu, Guoyu Pan, Chih‐Tsung Yang, Xiaohui Zhang, Shaojin Li, Zhaobin Guo, Hanyang Liu, Guangbo Ge   +13 more
wiley   +1 more source

Figure S3 from Monoclonal Antibodies Directed against Cadherin RGD Exhibit Therapeutic Activity against Melanoma and Colorectal Cancer Metastasis

, 2023
Rubén A. Bartolomé, Carmen Aizpurúa, Marta Jaén, Sofía Torres, Eva Calviño, Juan I. Imbaud, J. Ignacio Casal   +6 more
openalex   +1 more source

XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss

Advanced Science, EarlyView.
Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan, Yuhua Zhang, Jiawei Du, Yongjun Zhu, Wei Cao, Yongjie Wei, Han Wu, Shiyu Qiu, Shiyi Pan, Lian Chen, Pingping Liang, Renjie Chai, Jianming Yang, Qiaojun Fang   +13 more
wiley   +1 more source

1055 Bacterial Protein Azurin as a New Candidate Drug to Treat P-cadherin Overexpressing Breast Cancer

, 2012
Nuno Bernardes, Ana Sofia Ribeiro, Bruna Mota, T. Estevens, Rute G. Matos, Cecília M. Arraiano, Raquel Seruca, Jacobo Paredes, Arsénio M. Fialho   +8 more
openalex   +1 more source

Membrane Localization of Membrane Type 5 Matrix Metalloproteinase by AMPA Receptor Binding Protein and Cleavage of Cadherins [PDF]

, 2006
Sara Monea, Bryen A. Jordan, Sapna Srivastava, Sunita deSouza, Edward B. Ziff   +4 more
openalex   +1 more source

Evaluation of the clinicopathological significance of E-Cadherin and Ki 67 immuno-expression in triple negative breast cancer [PDF]

, 2023
Eman Esmail, Mohammed El-rashidy, Heba Mashhour, Hend Salah Abo-Safia   +3 more
openalex   +1 more source

Conformable Device for Independent Measurements of Mucosal and Vascular Barriers in a Complex In Vitro Intestinal Model

Advanced Science, EarlyView.
Development of more complex in vitro models necessitates the development of improved monitoring approaches. This work demonstrates a novel conformable device capable of measuring the resistance of two cell barriers within a single model independently, a significant advantage over conventional trans‐epithelial/endothelial electrical resistance (TEER ...
Alexandra Elisabeth Wheeler, Sonja Blasche, Rob Bradley, Rachana Acharya, Sophie Oldroyd, David Bulmer, Kiran R. Patil, Róisín Meabh Owens   +7 more
wiley   +1 more source

“Genetic and biochemical analysis of the regulation of N-Cadherin through the Arf-GEF Schizo and Arp2/3 complex mediated F-actin formation during myoblast fusion in Drosophila melanogaster”

, 2012
Verena Groth
openalex   +1 more source

Integration of Cadherin Adhesion and Cytoskeleton at Adherens Junctions.

Cold Spring Harbor Perspectives in Biology, 2017
R. Mége, N. Ishiyama
semanticscholar   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source