Results 181 to 190 of about 187,124 (218)

Protective effects of adiponectin receptor agonists against equine lamellar endoplasmic reticulum stress

Equine Veterinary Journal, EarlyView.
Abstract Background Lamellar endoplasmic reticulum (ER) stress occurs in hyperinsulinemia‐associated and sepsis‐related laminitis. Adiponectin is associated with reduced laminitis risk and inhibits ER stress in other species. Objectives To induce ER stress in ex vivo equine lamellar cells using pharmacological agents.
Marine A. Barnabé, Jonathan Elliott, Nicola J. Menzies‐Gow, Simon R. Bailey, Nicholas J. Bamford, Yu‐Mei Chang, Matthew C. Gage   +6 more
wiley   +1 more source

<i>CircARID1A</i> promotes gastric cancer progression by targeting the <i>miR-147a</i>/SNAI2 signaling axis. [PDF]

Cell Adh Migr
Guo K, Yan X, Liu X, Peng Y, Xu W.
europepmc   +1 more source

Micro/Nanostructured Materials and Microfluidic Diagnostic Platforms Enable Multimodal Detection of Circulating Tumor Cells

Exploration, EarlyView.
Engineered micro/nanomaterials enable high‐efficiency CTC capture, release, and multimodal molecular profiling. Integrated with AI‐driven analytics, these platforms decode tumor heterogeneity and metastatic dynamics, advancing real‐time monitoring and precision oncology through DNA, RNA, and protein cross‐scale data fusion.
Hao Li, Jiaojiao Sun, Kunguo Liu, Shijie Wang, Bowen Fu, Hong Zhu, Peng Cao, Xin Han   +7 more
wiley   +1 more source

Genkwanin mitigates renal fibrosis by reprogramming profibrotic signaling and restoring TFEB-mediated autophagy. [PDF]

Front Pharmacol
Wang S, He Y, Gan X, Kang H, Zhou Z, He Z.   +5 more
europepmc   +1 more source

Extracellular vesicles derived from edible plants and edible fungi: Compositional characteristics, engineering strategies and biofunctions

Food Biomacromolecules, EarlyView.
Non‐animal extracellular vesicles as bioactive‐compound carriers: compositional characteristics, engineering strategies, and biofunctions. Abstract Animal‐derived extracellular vesicles (EVs) were widely used for bioactive compound delivery but constrained by complex origins, potential immunogenicity, and pathogen contamination.
Jiahao Yu, Rongheng Chen, Yuxuan Liu, Yizhen Xie, Fangyu Fan, Simin Feng, Ping Shao   +6 more
wiley   +1 more source

Loss of Smad4 drives vascular malformations via c-KIT-dependent high-fluid shear stress mimicry. [PDF]

J Clin Invest
Gahn J, Wu F, Zhang Q, Di Y, Behera T, Ren Y, Hashemi Z, Banerjee K, Cordero J, Gherman C, Andorfer K, Seebauer CT, Mirzapour-Shafiyi F, Dobreva G, Schwartz MA, Ola R.   +15 more
europepmc   +1 more source

Propranolol attenuates the malignant biological behaviors of renal cancer cells partly through modulation of the IL-6/PI3K/AKT signaling axis. [PDF]

Front Pharmacol
Lu D, Xie X, Liu Y, Zhang T, Fan H, Liao S, Wu Y.   +6 more
europepmc   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Endothelial Exostosin-1 Is Needed for Glycocalyx Integrity and Inflammatory Resolution in Acute Lung Injury. [PDF]

FASEB J
Kawasaki Y, Tomita H, Suzuki K, Takada C, Asano H, Kano S, Wakayama Y, Fukuda H, Minamiyama T, Yoshimura G, Kamidani R, Kakino Y, Miura T, Kitagawa Y, Fukuta T, Miyake T, Suzuki A, Matsumoto K, Tetsuka N, Yoshida S, Maekawa Y, Yamaguchi Y, Okada H.   +22 more
europepmc   +1 more source