Results 191 to 200 of about 182,358 (260)

Oxidative Stress Induced Senescent Macrophage-Driven Squamous Cell Carcinoma Invasion via Glutamine Metabolic Reprogramming. [PDF]

Aging Cell
Wang S, Mu J, Zhao W, Hu C, Shi X, Zhou H, Liu J, Wu F.   +7 more
europepmc   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Low E-cadherin expression is associated with poor prognosis in pulmonal adenocarcinoma. [PDF]

Sci Rep
Gehrisch F, Schmid KA, Kluth M, Makrypidi-Fraune G, Möller K, Lennartz M, Bertram V, Lutz F, Steurer S, Busch P, Hantzsch-Kuhn B, Reck M, Olchers T, Ellebrecht DB, Fraune C, Simon R, Sauter G, von Weihe S.   +17 more
europepmc   +1 more source

Clinical and Molecular Features of BAP1‐Mutated Meningiomas: Case Series

Molecular Carcinogenesis, EarlyView.
ABSTRACT BRCA1‐associated protein 1 (BAP1)‐deficient meningiomas represent a clinically and molecularly distinct subgroup with variable histology and aggressive behavior that may not be fully captured by current grading criteria. The clinical spectrum of BAP1 alterations in meningiomas, including both somatic and germline contexts, remains incompletely
Ivan Pradilla, Rasha Alfattal, Susan L. McGovern, Shaan M. Raza, Franco DeMonte, Leomar Y. Ballester, Chirag B. Patel, Carlos Kamiya‐Matsuoka   +7 more
wiley   +1 more source

A pro-carcinogenic bacterial toxin binds claudin-4 to cleave E-cadherin. [PDF]

Nature
White MT, Wang K, Zhang H, Eckhard U, Hullahalli K, Chen J, Wu S, Geis AL, Zhang J, Queen J, Gomis-Ruth FX, Waldor MK, Dong M, Sears CL.   +13 more
europepmc   +1 more source

Breast Cancer‐Derived AZU1 Educates Neutrophils to Promote Tumor Progression and Metastasis Through PAD4‐Dependent Extracellular Trap Formation

Molecular Carcinogenesis, EarlyView.
ABSTRACT Neutrophil extracellular traps (NETs) play crucial roles in cancer progression, but their regulatory mechanisms in breast cancer remain poorly understood. We developed a NETs‐related prognostic risk model using TCGA breast cancer data and identified key biomarkers through bioinformatics analysis.
Zhen Huang, Zhe Wu, Guiyue Zhu, Fangyu Qiu, Lihui Li, Yujie Xie, Chunyu Wei, Yinhua Pan, Quanqing Zou, Yuntian Tang   +9 more
wiley   +1 more source

Konjac petroleum ether extract inhibits triple-negative breast cancer cell migration and invasion by attenuating <i>OLFML2A</i>-mediated epithelial-mesenchymal transition. [PDF]

Front Pharmacol
Chen Y, Yu Q, Ding H, Jiang W, Gao X.
europepmc   +1 more source

Multiomics Insights Into AL Amyloidosis

Medicine Bulletin, EarlyView.
ABSTRACT Light chain amyloidosis is a systemic or localized protein conformational disorder triggered by misfolded immunoglobulin light chains, leading to amyloid fibril deposition. The disease is characterized by multiorgan involvement and delayed diagnosis, contributing to poor prognosis and high mortality rates.
Zixuan Zhang, Ziru Huang, Haoxiang Tang, Xianrun Pan, Rong Wang, Dingding Zhang, Jian Huang   +6 more
wiley   +1 more source

Indole-3-acetic acid promotes differentiation while suppressing proliferation in human intestinal epithelial cells. [PDF]

Hum Cell
Mallardo M, Memon F, Pagliaro R, Daniele A, Nigro E.   +4 more
europepmc   +1 more source