Results 1 to 10 of about 1,062,506 (300)

Additional file 7: of RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling pathway and EMT in colorectal cancer

, 2019
Table S3. Relationship between RUNX1 mRNA expression and the clinicpathological features of CRC patients. (DOCX 14 kb)
Li, Qingyuan, Lai, Qiuhua, He, Chengcheng, Fang, Yuxin, Yan, Qun, Zhang, Yue, Wang, Xinke, Gu, Chuncai, Wang, Yiqing, Ye, Liangying, Han, Lu, Lin, Xin, Chen, Junsheng, Cai, Jianqun, Li, Aimin, Liu, Side   +15 more
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Supplementary Figure S1. Densitometric analysis of total β-catenin, active β-catenin, AurKA, p-AktSer473, p-GSK3βSer9 and p-Mcl-1Ser159 expression. from Loss of PKCδ Induces Prostate Cancer Resistance to Paclitaxel through Activation of Wnt/β-Catenin Pathway and Mcl-1 Accumulation

, 2023
<p>PKCÎ'-silenced PC3 (a) and LNCaP (b) cells were treated with DMSO or paclitaxel 2.5 µM 48 hours. Histograms show densitometric and statistical analysis of indicated proteins from panels (c) and (d) of the Figure 3. Data are presented as mean{plus minus}S.E.M.
Carmen Sáez, Miguel A. Japón, Francisco Romero, Begoña Pérez-Valderrama, Rafael Medina, Jessica Gasca, Carolina Castilla, M. Luz Flores   +7 more
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Transcriptional activity mediated by β-CATENIN and TCF/LEF family members is completely dispensable for survival and propagation of multiple human colorectal cancer cell lines

Scientific Reports, 2023
Unrestrained transcriptional activity of β-CATENIN and its binding partner TCF7L2 frequently underlies colorectal tumor initiation and is considered an obligatory oncogenic driver throughout intestinal carcinogenesis.
Janna Fröhlich, Katja Rose, Andreas Hecht   +2 more
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Additional file 1: of Parkin deficiency prevents chronic ethanol-induced hepatic lipid accumulation through β-catenin accumulation

, 2019
Table S1. Mouse oligonucleotide primers used for real time RT-PCR. Table S2. Human oligonucleotide primers used for real time RT-PCR. (DOC 34 kb)
Lee, Dong, Park, Mi, Hwang, Chul, Kim, Youngsoo, Hwang, Dae, Han, Sang, Hong, Jin   +6 more
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Additional file 1: of Enrichment of cancer stem cells via β-catenin contributing to the tumorigenesis of hepatocellular carcinoma

, 2018
Supplementary experiments and routine methods. Figure S1. Spheroid formation capability of HCC cell lines. Figure S2. β-catenin expression in HepG2 cell line. Figure S3. Knockdown efficiency of siRNA transfection. Routine Methods: Immunocytochemistry (ICC) Staining, Flow-Cytometry Analysis, Protein Extraction and Western Blot. Table S1.
Pandit, Harshul, Li, Yan, Li, Xuanyi, Zhang, Weizhong, Li, Suping, Martin, Robert   +5 more
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Additional file 6: of RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling pathway and EMT in colorectal cancer

, 2019
Table S2. Chip primer sequenced used for quantitative real-time PCR. (DOC 29 kb)
Li, Qingyuan, Lai, Qiuhua, He, Chengcheng, Fang, Yuxin, Yan, Qun, Zhang, Yue, Wang, Xinke, Gu, Chuncai, Wang, Yiqing, Ye, Liangying, Han, Lu, Lin, Xin, Chen, Junsheng, Cai, Jianqun, Li, Aimin, Liu, Side   +15 more
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Additional file 3 of β-Catenin nuclear localization positively feeds back on EGF/EGFR-attenuated AJAP1 expression in breast cancer

, 2019
Table S3. Cox proportional hazard regression model analysis. (DOC 36 kb)
Xu, Cong, Liu, Fang, Xiang, Guomin, Cao, Lu, Wang, Shuling, Liu, Jing, Meng, Qingxiang, Xu, Danni, Lv, Shuhua, Jiao, Jiao, Niu, Yun   +10 more
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Mitochondrial AK3 inhibits nuclear β-catenin localization and its activation through enhancing mitochondrial activity

Cell Death and Disease
The aberrant Wnt/β-catenin signaling is tightly associated with developmental disorders and tumorigenesis. However, spatial regulation of cytoplasmic β-catenin with regard to its nuclear accumulation and signaling activation remains poorly understood ...
Muhah Jeong, Shin-Hyeon Ryu, Young-Sin Cho, Do-Hyeong Na, Jongyeon Baek, Jihoon Nah, Ki Woo Kim, Yong-Keun Jung   +7 more
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MOESM2 of JMJD2C promotes colorectal cancer metastasis via regulating histone methylation of MALAT1 promoter and enhancing β-catenin signaling pathway

, 2019
Additional file 2: Figure S2. JMJD2C promoted the proliferation of CRC HCT116 cells, but affected little on the apoptosis of the indicated cells. a MTT assay of HCT116 cells transfected with shRNA/NT, shRNA/JMJD2C, empty vector, or JMJD2C overexpression vector, respectively.
Wu, Xinnan, Li, Ruixiao, Song, Qing, Zhang, Chengcheng, Jia, Ru, Han, Zhifen, Zhou, Lihong, Sui, Hua, Liu, Xuan, Zhu, Huirong, Yang, Liu, Wang, Yan, Ji, Qing, Li, Qi   +13 more
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Astragalus Inhibits Epithelial-to-Mesenchymal Transition of Peritoneal Mesothelial Cells by Down-Regulating β-Catenin

Cellular Physiology and Biochemistry, 2018
Background/Aims: The epithelial-to-mesenchymal transition (EMT) of peritoneal mesothelial cells (PMCs) is a crucial event in the induction of peritoneal fibrosis (PF), in which canonical Wnt/β-catenin signaling participates.
Manshu Yu, Jun Shi, Meixiao Sheng, Kun Gao, Lu Zhang, Li Liu, Yilin Zhu   +6 more
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