Results 271 to 280 of about 65,722 (350)

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

Desmoglein-driven dynamic signaling in pemphigus vulgaris: a systematic review of pathogenic pathways. [PDF]

NPJ Regen Med
Rahimi S, Hariton WVJ, Khalaj F, Ludwig RJ, Borradori L, Müller EJ.   +5 more
europepmc   +1 more source

RAB2A controls MT1‐MMP endocytic and E‐cadherin polarized Golgi trafficking to promote invasive breast cancer programs

, 2016
Hiroaki Kajiho, Yuko Kajiho, Emanuela Frittoli, Stefano Confalonieri, Giovanni Bertalot, Giuseppe Viale, Pier Paolo Di Fiore, Amanda Oldani, Massimiliano Garrè, Galina V. Beznoussenko, Andrea Palamidessi, Manuela Vecchi, Philippe Chavrier, Franck Perez, Giorgio Scita   +14 more
openalex   +2 more sources

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

Atypical Cadherin FAT2 Is Required for Synaptic Integrity and Motor Behaviors. [PDF]

J Neurosci
Wang X, Pu Y, Miao J, Xie L, Guan L, Cui Y, Wang J, Qin L, Han Y, Wöhr M, Zhang B.   +10 more
europepmc   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Emerging functions of Plakophilin 4 in the control of cell contact dynamics. [PDF]

Cell Commun Signal
Müller L, Hatzfeld M.
europepmc   +1 more source

Breaking Barriers: Characterization of the Intradermal Lipopolysaccharide Challenge as an In Vivo Model for Controlled Induction of Vascular Leakage in Healthy Volunteers

Clinical Pharmacology &Therapeutics, EarlyView.
Vascular leakage and its associated phenomena vasodilation and endothelial activation are pathophysiological features of various diseases. Multiple drug candidates targeting these phenomena are in development, necessitating translational models to demonstrate proof‐of‐pharmacology and proof‐of‐mechanism in early‐phase clinical trials.
Marella Cornelia Elizabeth van Ruissen, Menno van Diemen, Liza Botros, Ingrid Tomljanovic, Hind Achbo, Dimitra Eleftheriou, Paul Willem Schenk, Naomi Bertine Klarenbeek, Derek William Gilroy, Manon Aleida Adriana Jansen, Matthijs Moerland   +10 more
wiley   +1 more source

Engineering Cellular Self-Adhesions Inside 3D Printed Micro-Arches to Enhance Cell:Biomaterial Attachment. [PDF]

Adv Mater
Singh A, Kim HE, Rawson L, Miao M, Cohen DJ.   +4 more
europepmc   +1 more source

Differential sensitivity of midline development to mitosis during and after primitive streak extension

Developmental Dynamics, EarlyView.
Abstract Background Midline establishment is a fundamental process during early embryogenesis for Bilaterians. Midline morphogenesis in non‐amniotes can occur without mitosis, through Planar Cell Polarity (PCP) signaling. By contrast, amniotes utilize both cellular processes for developing the early midline landmark, the primitive streak (PS).
Zhiling Zhao, Rieko Asai, Takashi Mikawa
wiley   +1 more source