Results 251 to 260 of about 44,600 (299)
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Current Opinion in Cell Biology, 2002
New evidence from blocking desmosomal adhesion with anti-adhesion peptides reveals a role for desmosomes in cell positioning in morphogenesis. Desmosomal adhesion is necessary for the stability of adherens junctions in epithelial cell sheets. Knockout and mis-expression of desmosomal cadherins in mice suggests that they may function directly or ...
Garrod, David R. +2 more
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New evidence from blocking desmosomal adhesion with anti-adhesion peptides reveals a role for desmosomes in cell positioning in morphogenesis. Desmosomal adhesion is necessary for the stability of adherens junctions in epithelial cell sheets. Knockout and mis-expression of desmosomal cadherins in mice suggests that they may function directly or ...
Garrod, David R. +2 more
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Seminars in Cell Biology, 1992
Cadherins represent a gene family of Ca(2+)-dependent cell adhesion molecules (CAMs) identified during development and in adult organs. They generally mediate cell-cell adhesion by homotypic interaction, although heterotypic binding between different cadherin molecules is possible.
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Cadherins represent a gene family of Ca(2+)-dependent cell adhesion molecules (CAMs) identified during development and in adult organs. They generally mediate cell-cell adhesion by homotypic interaction, although heterotypic binding between different cadherin molecules is possible.
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2004
The presence of a functional E-cadherin/catenin cell-cell adhesion complex is a prerequisite for normal development and maintenance of epithelial structures in the mammalian body. This implies that the acquisition of molecular abnormalities that disturb the expression or function of this complex is related to the development and progression of most, if
K, Strumane, G, Berx, F, Van Roy
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The presence of a functional E-cadherin/catenin cell-cell adhesion complex is a prerequisite for normal development and maintenance of epithelial structures in the mammalian body. This implies that the acquisition of molecular abnormalities that disturb the expression or function of this complex is related to the development and progression of most, if
K, Strumane, G, Berx, F, Van Roy
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2004
The cadherin family of cell adhesion molecules has emerged as a key regulator of embryonic morphogenesis. Although we are beginning to learn more about the developmental functions of non-classic cadherins, most of our current knowledge of the involvement of cadherins in various cellular processes that guide morphogenesis, such as adhesion, migration ...
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The cadherin family of cell adhesion molecules has emerged as a key regulator of embryonic morphogenesis. Although we are beginning to learn more about the developmental functions of non-classic cadherins, most of our current knowledge of the involvement of cadherins in various cellular processes that guide morphogenesis, such as adhesion, migration ...
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Various Atypical Cadherins: T-Cadherin, RET, Calsyntenin, and 7D-Cadherin
2016In addition to the various cadherins described in previous chapters, there are several atypical cadherins that have unique structures and functions. Because of their great diversity, some cadherins have unexpected roles beyond cell–cell adhesion. In this chapter, we review interesting features of T-cadherin, RET, calsyntenins, and 7D-cadherins that ...
Keiko Imai-Okano, Shinji Hirano
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Molecular analysis of E‐cadherin and cadherin‐11 in Wilms' tumours
The Journal of Pathology, 2000Different studies of Wilms' tumours have demonstrated a loss of heterozygosity (LOH) of chromosome 16q ranging from 17 to 25%. In order to search for a potential tumour suppressor gene on 16q, we chose the calcium-dependent cell adhesion molecules E-cadherin and cadherin-11 as candidate genes, which are both located on the long arm of chromosome 16.
S, Schulz +8 more
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The Premetazoan Ancestry of Cadherins
Science, 2008Cadherin-mediated cell adhesion and signaling is essential for metazoan development and yet is absent from all other multicellular organisms. We found cadherin genes at numbers similar to those observed in complex metazoans in one of the closest single-celled relatives of metazoans, the choanoflagellate Monosiga brevicollis
Monika, Abedin, Nicole, King
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The cadherin superfamily database
Journal of Structural and Functional Genomics, 2002The cadherin superfamily is a large protein family with diverse structures and functions. Because of this diversity and the growing biological interest in cell adhesion and signaling processes, in which many members of the cadherin superfamily play a crucial role, it is becoming increasingly important to develop tools to manage, distribute and analyze ...
Kevin, Truong, Mitsuhiko, Ikura
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Cell and Tissue Research, 2014
Although being a monolayer the vascular endothelium controls fundamental vessel functions such as permeability, leukocyte extravasation and angiogenesis. The endothelial selective transmembrane constituent of adherens junctions, Vascular Endothelial- (VE-) cadherin plays a crucial role in the regulation of such activities.
L. Bravi, E. Dejana, M. G. Lampugnani
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Although being a monolayer the vascular endothelium controls fundamental vessel functions such as permeability, leukocyte extravasation and angiogenesis. The endothelial selective transmembrane constituent of adherens junctions, Vascular Endothelial- (VE-) cadherin plays a crucial role in the regulation of such activities.
L. Bravi, E. Dejana, M. G. Lampugnani
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Arteriosclerosis, Thrombosis, and Vascular Biology, 1995
Abstract Human vascular endothelial cadherin (VE-cadherin, 7B4/cadherin-5) is an endothelial-specific cadherin localized at the intercellular junctions. To directly investigate the functional role of this molecule we cloned the full-length cDNA from human endothelial cells and transfected its coding region into Chinese hamster ...
F, Breviario +9 more
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Abstract Human vascular endothelial cadherin (VE-cadherin, 7B4/cadherin-5) is an endothelial-specific cadherin localized at the intercellular junctions. To directly investigate the functional role of this molecule we cloned the full-length cDNA from human endothelial cells and transfected its coding region into Chinese hamster ...
F, Breviario +9 more
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