Results 241 to 250 of about 30,352 (298)

Nervous system-wide analysis of all <i>C. elegans</i> cadherins reveals neuron-specific functions across multiple anatomical scales. [PDF]

Sci Adv
Majeed M, Liao CP, Hobert O.
europepmc   +1 more source

A Pan‐Cancer Single‐Cell Atlas of Bone Metastases Reveals Convergent Malignant Programs and Coordinated Immune Dysfunction

iMetaMed, EarlyView.
A pan‐cancer atlas deciphers tumor‐induced reprogramming in bone metastases. Malignant evolution toward MYC/proliferation is a hallmark of bone metastases. Niche‐mediated immune dysfunction is characterized by immature pDCs, impaired antigen presentation and phagocytosis in TAMs, and exhausted T cells.
Yitong Pan, Zhou Yang, Junyuan Deng, Feng Liu, Guang Lei   +4 more
wiley   +1 more source

Cadherin-1-mediated communication at the leader-follower boundary controls mouse breast tumor organoid collective migration. [PDF]

Cell Rep
Morikis VA, Avila DB, DiMauro A, Cao Y, Hwang PY, Pathak A, Longmore GD.   +6 more
europepmc   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

In toto analysis of embryonic organisation reduces tissue diversity to two archetypes requiring specific cadherins. [PDF]

Nat Commun
Brambach M, Wittmann J, Albert M, Julmi J, Bill R, Gilmour D.   +5 more
europepmc   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Development of an anti-CDH15/M-cadherin monoclonal antibody Ca₁₅Mab-1 for flow cytometry, immunoblotting, and immunohistochemistry. [PDF]

Biochem Biophys Rep
Ubukata R, Suzuki H, Tanaka T, Kaneko MK, Kato Y.   +4 more
europepmc   +1 more source

Immune Checkpoint Inhibitors Induce Intestinal Epithelial Injury and a Senescence‐Like Phenotype

iNew Medicine, EarlyView.
ICI treatment promotes the infiltration of activated immune cells into the intestinal mucosa. This inflammatory microenvironment is associated with significant epithelial injury, characterized by the disruption of the epithelial barrier, the depletion of specialized secretory cell lineages, and the induction of a premature senescence phenotype ...
Juan Wang, Shuang Wu, Shuangbiao Wei, Weizhen Xiang, Jianshang Huang, Lei Xiong, Hua Wang, Li Zuo   +7 more
wiley   +1 more source

The emerging role of human transmembrane RGD-based counter-receptors of integrins in health and disease. [PDF]

Cell Mol Biol Lett
Cabañas C, Rossi E, Bartolomé RA, Doberstein K, Altevogt P, Casal JI, Bernabeu C.   +6 more
europepmc   +1 more source

Varying susceptibility of subpopulations along the epithelial-mesenchymal spectrum to undergo EMT. [PDF]

FEBS J
Jain P, Jolly MK.
europepmc   +1 more source