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Diagnostic Performance of CT/MRI LI-RADS Version 2018 Major Feature Combinations: Individual Participant Data Meta-Analysis.

Radiology
Background The CT/MRI Liver Imaging Reporting and Data System (LI-RADS) diagnostic algorithm classifies liver observations in patients with high-risk hepatocellular carcinoma (HCC) using imaging features.
Robert G. Adamo   +52 more
semanticscholar   +1 more source

TransplantLines, a biobank and cohort study of solid organ transplant recipients and donors

European Journal of Epidemiology
The TransplantLines Biobank and Cohort Study (NCT03272841) is an ongoing prospective study conducted at the University Medical Centre Groningen, The Netherlands. TransplantLines aims to identify risk factors and biomarkers associated with health problems
A. M. Posthumus   +64 more
semanticscholar   +1 more source

Preliminary Study of Spontaneous Micronuclei and Hematology Profile of Workers Exposed to Low-Dose Radiation

Asian Pacific Journal of Cancer Prevention
Objective: This study aims to evaluate the conditions suffered by radiation workers based on the concerned indication of complete blood tests and genotoxicity using genomic biomarkers of micronuclei.
Y. Lusiyanti   +8 more
semanticscholar   +1 more source

Calciprotein particle-activated endothelial cells aggravate smooth muscle cell calcification via paracrine signalling

Cellular and Molecular Life Sciences
Vascular calcification is highly prevalent in Chronic Kidney Disease (CKD) and is associated with markedly increased cardiovascular risk. High serum phosphate in CKD increases calcification propensity via generation of circulating calciprotein particles (
Lian Feenstra   +61 more
semanticscholar   +1 more source

A Toolkit for Creating Intelligent Virtual Humans in Extended Reality

2025 IEEE Conference on Virtual Reality and 3D User Interfaces Abstracts and Workshops (VRW)
This paper introduces an initial implementation and a preliminary evaluation of a toolkit for providing Intelligent Virtual Humans in Extended Reality (XR) environments.
Fariba Mostajeran   +16 more
semanticscholar   +1 more source

Pharmacometabolomics Detects Various Unreported Metoprolol Metabolites in Urine of (Potential) Living Kidney Donors and Kidney Transplant Recipients

Clinical Pharmacokinetics
Metoprolol is primarily metabolized via the polymorphic cytochrome P450-2D6 (CYP2D6) enzyme, which underlies interindividual variation in conversion rates and may benefit from pharmacogenetics-driven therapy personalization.
Wietske A. Heddema   +49 more
semanticscholar   +1 more source

Metabolic Signatures in Lung Cancer: Prognostic Value of Acid–Base Disruptions and Serum Indices

International Journal of Molecular Sciences
One characteristic of tumor cells is the increased anaerobic metabolism through glycolysis leading to an acidic environment of the tumor. This acidity is linked to tumor progression, invasion and metastasis, besides stimulated survival pathways in the ...
F. Ponholzer   +8 more
semanticscholar   +1 more source

Torque Teno Virus Loads and Leukocyte Populations in Stable Outpatient Solid Organ Transplant Recipients.

International Journal of Infectious Diseases
OBJECTIVES Torque teno virus (TTV) is proposed as a biomarker of immune function, potentially aiding in personalized immunosuppressive dosing after solid organ transplantation. TTV is thought to replicate in leukocytes, particularly immature granulocytes.
J. Jonker   +14 more
semanticscholar   +1 more source

Application of the project based learning model based on lesson study to improve Students' critical thinking skills

Edunity Kajian Ilmu Sosial dan Pendidikan
This research aims to enhance critical thinking skills using the Lesson research-based project-based learning (PjBL) model in improving the critical thinking skills of grade VII students in social studies subjects at SMP Negeri 4 Ciawigebang.
Rani Tania Pratiwi   +7 more
semanticscholar   +1 more source

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