Results 81 to 90 of about 1,674 (141)

TransplantLines, a biobank and cohort study of solid organ transplant recipients and donors

European Journal of Epidemiology
The TransplantLines Biobank and Cohort Study (NCT03272841) is an ongoing prospective study conducted at the University Medical Centre Groningen, The Netherlands. TransplantLines aims to identify risk factors and biomarkers associated with health problems
A. M. Posthumus, T. Knobbe, D. Kremer, A. Gomes-Neto, Isabelle J. C. Dielwart, J. Jonker, C. Doorenbos, M. Eisenga, M. van Londen, R. Douwes, L. M. Nieuwenhuis, C. Annema, M. T. de Boer, M. de Borst, K. Damman, Robert A. Pol, C. Gan, Erik A. M. Verschuuren, H. Blokzijl, V. E. de Meijer, S. J. Bakker, Coby Stefan P. Hans Frank A. J. A. Marieke T. Kevin Mar Annema Berger Blokzijl Bodewes de Boer Damman de B, C. Annema, Stefan P Berger, H. Blokzijl, F. Bodewes, M. T. de Boer, K. Damman, M. de Borst, A. Diepstra, G. Dijkstra, R. Douwes, C. Doorenbos, M. Eisenga, M. Erasmus, C. Gan, A. Gomes-Neto, E. Hak, B. Hepkema, M. C. van den Heuvel, J. Jonker, F. Klont, T. Knobbe, D. Kremer, C. V. Van Leer-Buter, H. Leuvenink, M. van Londen, W. Lexmond, V. E. de Meijer, H. Niesters, Gertrude J. Nieuwenhuis-Moeke, L. V. van Pelt, Robert A. Pol, A. M. Posthumus, A. Ranchor, Jan-Stephan F. Sanders, M. Siebelink, Riemer J. H. J. A. Slart, J. Swarte, D. Touw, C. A. Velde-Keyzer, Erik A. M. Verschuuren, M. Vos, R. Weersma, S. J. Bakker   +64 more
semanticscholar   +1 more source

Calciprotein particle-activated endothelial cells aggravate smooth muscle cell calcification via paracrine signalling

Cellular and Molecular Life Sciences
Vascular calcification is highly prevalent in Chronic Kidney Disease (CKD) and is associated with markedly increased cardiovascular risk. High serum phosphate in CKD increases calcification propensity via generation of circulating calciprotein particles (
Lian Feenstra, Lara W. Zeper, Brenda van de Langenberg, E. Kahlman, Guido de La Roij, M. Reijrink, Benoît Bernay, Laurent Chatre, J. Kuipers, B. Giepmans, Mirjam F Mastik, W. Kooistra, Monique E. Lodewijk, Malou Zuidscherwoude, Robert A. Pol, Coby Stephan J. L. Stefan P. Hans Frank A. J. A. Mariek Annema Bakker Berger Blokzijl Bodewes de Boer Damm, C. Annema, S. Bakker, S. Berger, H. Blokzijl, F. Bodewes, M. T. de Boer, K. Damman, M. de Borst, A. Diepstra, G. Dijkstra, R. Douwes, C. Doorenbos, M. Eisenga, M. Erasmus, C. Gan, A. G. Gomes Neto, E. Hak, B. Hepkema, M. C. van den Heuvel, F. Klont, T. Knobbe, D. Kremer, C. V. Van Leer-Buter, H. Leuvenink, M. van Londen, W. Lexmond, V. E. de Meijer, H. Niesters, Gertrude J. Nieuwenhuis-Moeke, L. V. van Pelt, Robert J. Porte, A. Ranchor, Jan-Stephan F. Sanders, M. Siebelink, Riemer J. H. J. A. Slart, J. Swarte, D. Touw, C. T. Te Velde-Keyzer, Erik A. M. Verschuuren, M. Vos, R. Weersma, Edward R Smith, G. Krenning, J. D. de Baaij, J. Hillebrands, J. Hoenderop   +61 more
semanticscholar   +1 more source

Preliminary Study of Spontaneous Micronuclei and Hematology Profile of Workers Exposed to Low-Dose Radiation

Asian Pacific Journal of Cancer Prevention
Objective: This study aims to evaluate the conditions suffered by radiation workers based on the concerned indication of complete blood tests and genotoxicity using genomic biomarkers of micronuclei.
Y. Lusiyanti, D. Tetriana, Viria Agesti Suvifan, T. Kisnanto, D. Yusuf, Caecilia Tuti Budiantari, H. N. E. Surniyantoro, I. Basri, S. Purnami   +8 more
semanticscholar   +1 more source

Dual Inhibition of SRC Family Kinases and Sorafenib Enhances Anti-Tumor Activity in Hepatocellular Carcinoma Cells

International Journal of Molecular Sciences
Hepatocellular carcinoma (HCC) remains a major clinical challenge due to its high recurrence rate and limited response to monotherapies, such as sorafenib—the standard first-line therapy for advanced HCC.
L. K. Cabral, C. Disoma, P. Tarchi, Korri E. El-Khobar, A. Agustiningsih, F. Dituri, C. Tiribelli, C. Sukowati   +7 more
semanticscholar   +1 more source

Pharmacometabolomics Detects Various Unreported Metoprolol Metabolites in Urine of (Potential) Living Kidney Donors and Kidney Transplant Recipients

Clinical Pharmacokinetics
Metoprolol is primarily metabolized via the polymorphic cytochrome P450-2D6 (CYP2D6) enzyme, which underlies interindividual variation in conversion rates and may benefit from pharmacogenetics-driven therapy personalization.
Wietske A. Heddema, Marieke A. J. Hof, Piotr Sosnowski, S. Bakker, G. Hopfgartner, F. Klont, Coby Stephan J. L. Stefan P. Hans Frank A. J. A. Mariek Annema Bakker Berger Blokzijl Bodewes de Boer Damm, C. Annema, S. Bakker, S. Berger, H. Blokzijl, F. Bodewes, M. T. de Boer, K. Damman, M. de Borst, A. Diepstra, G. Dijkstra, C. Doorenbos, R. Douwes, M. Eisenga, M. Erasmus, C. Gan, A. W. Gomes, E. Hak, B. Hepkema, J. Jonker, F. Klont, T. Knobbe, D. Kremer, H. Leuvenink, W. Lexmond, V. E. de Meijer, H. Niesters, Gertrude J. Nieuwenhuijs-Moeke, L. Joost van Pelt, R. Pol, A. M. Posthumus, A. Ranchor, Jan-Stephan F. Sanders, M. Siebelink, Riemer J. H. J. A. Slart, J. C. Swarte, D. Touw, M. C. van den Heuvel, C. V. Van Leer-Buter, M. van Londen, Charlotte A. te Velde Keyzer, Erik A. M. Verschuuren, M. Vos, R. Weersma   +49 more
semanticscholar   +1 more source

Metabolic Signatures in Lung Cancer: Prognostic Value of Acid–Base Disruptions and Serum Indices

International Journal of Molecular Sciences
One characteristic of tumor cells is the increased anaerobic metabolism through glycolysis leading to an acidic environment of the tumor. This acidity is linked to tumor progression, invasion and metastasis, besides stimulated survival pathways in the ...
F. Ponholzer, Marie-Christin Neuschmid, Helga Komi, C. Bogensperger, C. Ng, H. Maier, P. Lucciarini, S. Schneeberger, F. Augustin   +8 more
semanticscholar   +1 more source

A Toolkit for Creating Intelligent Virtual Humans in Extended Reality

2025 IEEE Conference on Virtual Reality and 3D User Interfaces Abstracts and Workshops (VRW)
This paper introduces an initial implementation and a preliminary evaluation of a toolkit for providing Intelligent Virtual Humans in Extended Reality (XR) environments.
Fariba Mostajeran, Ke Li, S. Rings, Lucie Kruse, Erik Wolf, Susanne Schmidt, Michael Arz, Joan Llobera, Pierre Nagorny, C. Charbonnier, Hannes Fassold, X. Alvarez, André Tavares, Nuno Santos, J. Orvalho, Sergi Fernández, Frank Steinicke   +16 more
semanticscholar   +1 more source

Pengaruh Faktor Internal dan Makroekonomi Terhadap Underpricing Saham IPO di Bursa Efek Indonesia: Pendekatan Sektoral Tahun 2022–2024

Journal of Accounting and Finance Management
Tujuan dari penelitian ini adalah untuk menganalisis pengaruh Financial Leverage Perusahaan (DER), Reputasi Underwriter, Ukuran Perusahaan, Kinerja Keuangan Perusahaan (ROA), Inflasi, Produk Domestik Bruto (PDB), dan Suku Bunga terhadap fenomena ...
Caecilia Wenehen, Mahjus Ekananda, Juliana Safitri   +2 more
semanticscholar   +1 more source

Low Dietary Iodine Intake and Sex-Specific Mortality in Kidney Transplant Recipients.

American Society of Nephrology. Clinical Journal
KEY POINTS Inadequate iodine intake is common among kidney transplant recipients, particularly in women. Among female kidney transplant recipients, inadequate iodine intake and lower urinary iodine excretion were independently associated with higher ...
Yvonne van der Veen, A. Post, D. Kremer, Jiasi Hao, C. Doorenbos, T. Knobbe, M. D. de Borst, D. Touw, Casper F M Franssen, E. Corpeleijn, C. Annema, S. J. Bakker   +11 more
semanticscholar   +1 more source

Torque Teno Virus Loads and Leukocyte Populations in Stable Outpatient Solid Organ Transplant Recipients.

International Journal of Infectious Diseases
OBJECTIVES Torque teno virus (TTV) is proposed as a biomarker of immune function, potentially aiding in personalized immunosuppressive dosing after solid organ transplantation. TTV is thought to replicate in leukocytes, particularly immature granulocytes.
J. Jonker, C. Doorenbos, E. Gore, A. Gomes-Neto, V. E. de Meijer, H. Blokzijl, Erik A. M. Verschuuren, C. Gan, Jan-Stephan F. Sanders, J. Linssen, S. Klatte, L. V. van Pelt, C.L. van Leer-Buter, S. J. Bakker, T. Investigators   +14 more
semanticscholar   +1 more source