Results 151 to 160 of about 148,951 (345)

Neuroprotective Potential of the Flavonoids Quercetin and Epicatechin in a C. elegans Tauopathy Model

open access: yesMolecular Nutrition &Food Research, EarlyView.
Epicatechin and quercetin enhanced healthspan in the C. elegans BR5270 tauopathy model, associated with the upregulation of autophagy‐related and α‐tubulin synthesis genes, and the downregulation of genes involved in the unfolded protein response. ABSTRACT The prevalence of cognitive disorders such as Alzheimer's disease (AD) is increasing due to the ...
Lidia Garzón‐García   +4 more
wiley   +1 more source

Top‐Down Proteomics: Why and When?

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Manifold biological processes at all levels of transcription and translation can lead to the formation of a high number of different protein species (i.e., proteoforms), which outnumber the sequences encoded in the genome by far. Due to the large number of protein molecules formed in this way, which span an enormous range of different ...
Philipp T. Kaulich, Andreas Tholey
wiley   +1 more source

mec-7 is a beta-tubulin gene required for the production of 15-protofilament microtubules in Caenorhabditis elegans. [PDF]

open access: gold, 1989
Cathy Savage‐Dunn   +5 more
openalex   +1 more source

Interactions of rare earth elements with living organisms and emerging biotechnical applications

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Rare earth elements (REEs) are critical resources required to achieve net‐zero carbon emission targets and energy security. However, rising demand for REEs coupled with significant extraction and processing challenges and geopolitical risks restricts access to REE resources.
Samantha A. McGaughey   +6 more
wiley   +1 more source

Supervised Learning of Protein Melting Temperature: Cross‐Species vs. Species‐Specific Prediction

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Protein melting temperatures are important proxies for stability, and frequently probed in protein engineering campaigns, for instance for enzyme discovery and protein optimization. With the emergence of large datasets of melting temperatures for diverse natural proteins, it has become possible to train models to predict this quantity, and the
Sebastián García López   +2 more
wiley   +1 more source

The continuing significance of chiral agrochemicals

open access: yesPest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

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