Results 181 to 190 of about 100,650 (200)
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Immunity in Caenorhabditis elegans
Current Opinion in Immunology, 2004Until very recently it was not known whether the invertebrate Caenorhabditis elegans was capable of mounting a specific immune response to protect itself from pathogens. It has only just become clear that this simple nematode in fact possesses a complex innate immune system, involving multiple signalling pathways and an armoury of antimicrobial ...
Anne Millet, Jonathan J. Ewbank
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Development Genes and Evolution, 2006
Studies of sterile mutants in Caenorhabditis elegans have uncovered new insights into fundamental aspects of gamete cell biology, development, and function at fertilization. The genome sequences of C. elegans, Caenorhabditis briggsae and Caenorhabditis remanei allow for informative comparative studies among these three species.
Rajesh Patel +5 more
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Studies of sterile mutants in Caenorhabditis elegans have uncovered new insights into fundamental aspects of gamete cell biology, development, and function at fertilization. The genome sequences of C. elegans, Caenorhabditis briggsae and Caenorhabditis remanei allow for informative comparative studies among these three species.
Rajesh Patel +5 more
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Transgenesis in Caenorhabditis elegans
2009Two efficient strategies have been developed and are widely used for the genetic transformation of the nematode Caenorhabditis elegans, DNA microinjection, and DNA-coated microparticle bombardment. Both methodologies facilitate the delivery of exogenous DNA into the developing oocytes of adult hermaphrodite animals, which then generate transgenic worms
Nikos Kourtis +3 more
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The kinetochores of Caenorhabditis elegans
Chromosoma, 1982Light microscopy of the mitotic chromosomes of Caenorhabditis elegans suggests that non-localized kinetochores are present, since the chromosomes appear as stiff rods 1 to 2 micrometers in length and lack any visible constriction. The holokinetic structure was confirmed by reconstructions of electron micrographs of dividing nuclei in serially sectioned
J. Nichol Thomson +2 more
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The microRNAs of Caenorhabditis elegans
Seminars in Cell & Developmental Biology, 2010The soil nematode, Caenorhabditis elegans, occupies a central place in the short history of microRNA (miRNA) research. The converse is also true: miRNAs have emerged as key regulatory components in the life cycle of the worm, as well as numerous other organisms.
Eric A. Miska +2 more
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Four Acetylcholinesterase Genes in the Nematodes caenorhabditis Elegans and Caenorhabditis Briggsae
1998It was reported that three genes ace-1, ace-2 and ace-3 located respectively on chromosomes X, I and II, encode three pharmacological classes of acetylcholinesterase (A, B and C) in the nematode Caenorhabditis elegans. We have cloned these genes and studied the expression of ace-1 and ace-2 using GFP reporter constructs.
Emmanuel Culetto +8 more
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The Caenorhabditis elegans lipidome
Archives of Biochemistry and Biophysics, 2016Lipids play important roles in biology, ranging from building blocks of membranes to signaling lipids. The nematode and model organism Caenorhabditis elegans has been used to explore lipid metabolism and several techniques for their analysis have been employed.
Michael Witting +1 more
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Caenorhabditis elegans development
Current Opinion in Cell Biology, 1989Developmental studies continue to be the primary focus of research on the nematode Caenorhabditis elegang and, as in the past, genetic analysis has been the principle tool for dissecting developmental phenomena. Major advances in the study of early embryogenesis, sex determination, cell lineages and cellular differentiation have resulted from the ...
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Chapter 30 Autophagy in Caenorhabditis elegans
2008Autophagy (cellular self-eating) is a highly regulated, lysosome-mediated catabolic process of eukaryotic cells to segregate by a special membrane and subsequently degrade their own constituents during development or starvation. Electron microscopy analysis reveals autophagic elements in various cell types of the nematode Caenorhabditis elegans, whose ...
Attila L. Kovács +6 more
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Biolistic Transformation of Caenorhabditis elegans
2012The ability to generate transgenic animals to study gene expression and function is a powerful and important part of the Caenorhabditis elegans genetic toolbox. Transgenic animals can be created by introducing exogenous DNA into the worm germline either by microinjection or by microparticle bombardment (biolistic transformation).
Eugene Berezikov, Meltem Isik
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