Results 271 to 280 of about 121,076 (308)
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Paramyosin of Caenorhabditis elegans
Journal of Molecular Biology, 1974Abstract Paramyosin has been isolated from the nematode, Caenorhabditis elegans . Its identity has been established by a variety of criteria, including purification, molecular weight, immunological cross reactivity with known paramyosin and formation of characteristic paracrystals.
R H, Waterston, H F, Epstein, S, Brenner
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Genetics of Aging in Caenorhabditis elegans
PLoS Genetics, 2007 A dissection of longevity in Caenorhabditis elegans reveals that animal life span is influenced by genes, environment, and stochastic factors. From molecules to physiology, a remarkable degree of evolutionary conservation is seen.
Adam Antebi
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Immunity in Caenorhabditis elegans
Current Opinion in Immunology, 2004Until very recently it was not known whether the invertebrate Caenorhabditis elegans was capable of mounting a specific immune response to protect itself from pathogens. It has only just become clear that this simple nematode in fact possesses a complex innate immune system, involving multiple signalling pathways and an armoury of antimicrobial ...
Anne C M, Millet, Jonathan J, Ewbank
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The kinetochores of Caenorhabditis elegans
Chromosoma, 1982Light microscopy of the mitotic chromosomes of Caenorhabditis elegans suggests that non-localized kinetochores are present, since the chromosomes appear as stiff rods 1 to 2 micrometers in length and lack any visible constriction. The holokinetic structure was confirmed by reconstructions of electron micrographs of dividing nuclei in serially sectioned
D G, Albertson, J N, Thomson
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Transgenesis in Caenorhabditis elegans
2009Two efficient strategies have been developed and are widely used for the genetic transformation of the nematode Caenorhabditis elegans, DNA microinjection, and DNA-coated microparticle bombardment. Both methodologies facilitate the delivery of exogenous DNA into the developing oocytes of adult hermaphrodite animals, which then generate transgenic worms
Matthias, Rieckher +3 more
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The microRNAs of Caenorhabditis elegans
Seminars in Cell & Developmental Biology, 2010The soil nematode, Caenorhabditis elegans, occupies a central place in the short history of microRNA (miRNA) research. The converse is also true: miRNAs have emerged as key regulatory components in the life cycle of the worm, as well as numerous other organisms.
Ethan J, Kaufman, Eric A, Miska
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Optogenetics in Caenorhabditis elegans
2015With a compact neural circuit consisting of entirely mapped 302 neurons, Caenorhabditis elegans plays an important role in the development and application of optogenetics. Optogenetics in C. elegans offers the opportunity that drastically changes experimental designs with increasing accessibility for neural activity and various cellular processes ...
Yuki, Tsukada, Ikue, Mori
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Caenorhabditis elegans development
Current Opinion in Cell Biology, 1989Developmental studies continue to be the primary focus of research on the nematode Caenorhabditis elegang and, as in the past, genetic analysis has been the principle tool for dissecting developmental phenomena. Major advances in the study of early embryogenesis, sex determination, cell lineages and cellular differentiation have resulted from the ...
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Four Acetylcholinesterase Genes in the Nematodes caenorhabditis Elegans and Caenorhabditis Briggsae
1998It was reported that three genes ace-1, ace-2 and ace-3 located respectively on chromosomes X, I and II, encode three pharmacological classes of acetylcholinesterase (A, B and C) in the nematode Caenorhabditis elegans. We have cloned these genes and studied the expression of ace-1 and ace-2 using GFP reporter constructs.
Culetto, E. +6 more
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Biolistic Transformation of Caenorhabditis elegans
2012The ability to generate transgenic animals to study gene expression and function is a powerful and important part of the Caenorhabditis elegans genetic toolbox. Transgenic animals can be created by introducing exogenous DNA into the worm germline either by microinjection or by microparticle bombardment (biolistic transformation).
Isik, M., Berezikov, E.
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