Allelic Variation at tRNA Genes in Three Nematode Species Indicates Mutation Load Despite Strong Purifying Selection. [PDF]
Bell AD +6 more
europepmc +1 more source
ABSTRACT Although it had been reported that the translation product of the functional aquaporin gene, aqp1, is localized to the contractile vacuole complex of Paramecium multimicronucleatum, the molecules that pass through this channel protein had not been identified. In the present study, we introduced and expressed this protein in Xenopus oocytes and
Masaki Ishida +5 more
wiley +1 more source
Dissecting GPCR Contributions to Gαo-Dependent Motor Dysfunction in <i>GNAO1</i>-Related Disorders Using <i>Caenorhabditis elegans</i>. [PDF]
Di Rocco M +12 more
europepmc +1 more source
This 15‐year bibliometric study (2009–2024) characterizes the global landscape of liquid–liquid phase separation (LLPS) in neurodegenerative diseases. We delineate the field's evolution from fundamental biophysics to clinical translation, emphasizing the liquid‐to‐solid transition of proteins like TDP‐43, tau, and α‐synuclein.
Chanyuan Zhang +6 more
wiley +1 more source
Bacteria producing the bioplastic polyhydroxybutyrate kill the nematode Caenorhabditis elegans. [PDF]
Giese GE +7 more
europepmc +1 more source
Structure‐informed engineering of plant–microbe interactions
SUMMARY This review critically evaluates how structural biology has enabled interface‐informed engineering of plant–microbe interactions, with a clear emphasis on the relative maturity of plant–pathogen research compared with symbiosis engineering. In plant immunity, atomic resolution structures of apoplastic receptors, host targets, and intracellular ...
Gloria Meng‐Hsuan Lin +2 more
wiley +1 more source
A Stress-Responsive Nuclear Factor, GLDI-8, Mediates Mitochondrial Stress Responses to ETC Dysfunction. [PDF]
Wu Y, Tang H.
europepmc +1 more source
Microgravity (μG) reduces mechanical tactile stimulation in Caenorhabditis elegans, causing neuromuscular decline, altered gene expression, synaptic defects, and accelerated aging phenotypes. The gentle‐touch mechanoreceptor MEC‐4 mediates μG‐induced body length reduction and extracellular matrix gene downregulation.
Atsushi Higashitani +16 more
wiley +1 more source
Proteome-based investigation of O-GlcNAcylation in a C. elegans model of ageing and Alzheimer's disease: Functional support for earlier hypothesis-generating findings. [PDF]
Garcia Olivera F.
europepmc +1 more source
Optimal male fertility and fecundity in Caenorhabditis elegans require Microprocessor and Argonaute gene function. [PDF]
Lu L, Rios C, Abbott AL.
europepmc +1 more source

