Results 91 to 100 of about 279,189 (378)

Prolonged quiescence delays somatic stem cell-like divisions in Caenorhabditis elegans and is controlled by insulin signaling [PDF]

, 2020
Cells can enter quiescence in adverse conditions and resume proliferation when the environment becomes favorable. Prolonged quiescence comes with a cost, reducing the subsequent speed and potential to return to proliferation. Here, we show that a similar
Artal-Sanz, Marta, Fernández-Yáñez, Antonio, García-Sánchez, Sabas, Mata-Cabana, Alejandro, Merrow, Martha, Olmedo, María, Rodríguez-Palero, María Jesús   +6 more
core   +1 more source

NAD+‐Boosters Improve Mitochondria Quality Control In Parkinson's Disease Models Via Mitochondrial UPR

Advanced Science, EarlyView.
Treatment of MPTP‐incubated cells with NAD+‐boosters increase the UPRmt/mitophagy‐related mitochondria quality control (MQC). Disturbed plasma UPRmt‐mitophagy‐mediated MQC profiles in PD patient samples. NMN inhibits motor deficit and forestalls neuropathology phenotypes of PD mice, which is required the atf4‐medicated UPRmt pathway.
Shuoting Zhou, Xi Xiong, Jialong Hou, Qi Duan, Yi Zheng, Tao Jiang, Jiani Huang, Haijun He, Jiaxue Xu, Keke Chen, Wenwen Wang, Jinlai Cai, Jingjing Qian, Huijun Chen, Weihong Song, XinShi Wang, Chenglong Xie   +16 more
wiley   +1 more source

Measurement of Lysosomal Size and Lysosomal Marker Intensities in Adult Caenorhabditis elegans

Bio-Protocol, 2018
Assays have been developed to study trafficking in various tissues of Caenorhabditis elegans. Adult C. elegans intestinal cells are large and have extensive endocytic networks, thus making them a good system for deciphering the endocytic pathway using ...
Julie Huynh, Hope Dang, Hanna Fares
doaj   +1 more source

Postembryonic RNAi in Heterorhabditis bacteriophora: a nematode insect parasite and host for insect pathogenic symbionts [PDF]

, 2007
Background: Heterorhabditis bacteriophora is applied throughout the world for the biological control of insects and is an animal model to study interspecies interactions, e.g. mutualism, parasitism and vector-borne disease. H. bacteriophora nematodes are
Ciche, Todd A., Sternberg, Paul W.
core   +4 more sources

The Caenorhabditis elegans Lifespan Machine [PDF]

Nature Methods, 2013
The measurement of lifespan pervades aging research. Because lifespan results from complex interactions between genetic, environmental and stochastic factors, it varies widely even among isogenic individuals. The actions of molecular mechanisms on lifespan are therefore visible only through their statistical effects on populations.
Walter Fontana, Bryne Ulmschneider, Nicholas Stroustrup, Javier Apfeld, Zachary M. Nash, Isaac F. López-Moyado   +5 more
openaire   +3 more sources

Alistipes senegalensis is Critically Involved in Gut Barrier Repair Mediated by Panax Ginseng Neutral Polysaccharides in Aged Mice

Advanced Science, EarlyView.
An integral functional axis through which GPN and functional metabolites of Alistipes senegalensis can hydrolyze tryptophan into indoles. Furthermore, the Alistipes senegalensis‐indole‐AhR pathway is found to be associated with increased expression of tight junction‐associated proteins and activation of gut stem cells.
Dandan Wang, Hui Wang, Yingna Li, Jing Lu, Xiaolei Tang, Dan Yang, Manying Wang, Daqing Zhao, Fangbing Liu, Shuai Zhang, Liwei Sun   +10 more
wiley   +1 more source

High‐Specificity Spatiotemporal Cholesterol Detection by Quadrature Phase‐Shifted Polarization Stimulated Raman Imaging

Angewandte Chemie, EarlyView.
Utilizing quadrature phase modulation, the phase‐shifted polarization SRS (QP2‐SRS) microscope enables simultaneous measurement of the ρ‐related χ1111(3)$\chi _{1111}^{( 3 )}$ and χ1221(3)$\chi _{1221}^{( 3 )}$ components. In cholesterol molecular measurements, QP2‐SRS leverages the structural differences between cholesterol and other biomolecules to ...
Yongqing Zhang, Xinyu Deng, Siming Wang, Wenyu Zhou, Zhengyan Wu, Xiaobin Tang, Hyeon Jeong Lee, Delong Zhang   +7 more
wiley   +2 more sources

Lipidomic Analysis of Caenorhabditis elegans Embryos

Bio-Protocol, 2017
Metabolomic is an emerging field of system biology. Lipidomic, a branch of metabolomic, aims to characterize lipophilic metabolites in biological systems. Caenorhabditis elegans (C. elegans) is a genetically tractable and versatile animal model for novel
Hung-Chi Yang, Cheng-Yu Hung, Yi-Yun Pan, Szecheng Lo, Daniel Chiu   +4 more
doaj   +1 more source

The microbial zoo in the C. elegans intestine: Bacteria, fungi and viruses [PDF]

, 2016
Press freedom has become one of the major challenges facing Journalism practice in the world. This paper explores the factors hindering press freedom in Nigeria using some relevant examples.
Jiang, Hongbing, Wang, David
core   +3 more sources

NECROTIC NEURODEGENERATION IN CAENORHABDITIS ELEGANS

TheScientificWorldJOURNAL, 2001
Necrosis plays a central role in neuronal injury associated with stroke and ischemia. Unlike apoptotic cell death, little is understood of molecular mechanisms of necrosis. The two distinct forms of cell death, necrosis and apoptosis, are easily distinguishable by morphological characteristics in the nematode Caenorhabditis elegans.
Monica Driscoll, Keli Xu, Beate Gerstbrein   +2 more
openaire   +3 more sources