Results 101 to 110 of about 193,403 (293)
Data in Brief, 2018 This article presents small RNA sequencing data of Caenorhabditis elegans consist of P0 control worms (untreated), P0 worms treated with a plant alkaloid, sanguinarine, and its F3 offspring.
Yit-Lai Chow, Fumihiko Sato
doaj
Cytoskeleton, EarlyView.ABSTRACT Cells have an intrinsic ability to rapidly respond to environmental change to regulate cell cycle progression and membrane organisation, thereby affecting cell growth and division. The actin cytoskeleton is a highly dynamic complex of proteins that can rapidly reorganise to change the growth pattern of a cell.
Holly R. Brooker +7 more
wiley +1 more source
Disruption of insulin signalling preserves bioenergetic competence of mitochondria in ageing Caenorhabditis elegans [PDF]
, 2010 Background: The gene daf-2 encodes the single insulin/insulin growth factor-1-like receptor of Caenorhabditis elegans. The reduction-of-function allele e1370 induces several metabolic alterations and doubles lifespan.
Braeckman, Bart +4 more
core +3 more sources
PLK4: Master Regulator of Centriole Duplication and Its Therapeutic Potential
Cytoskeleton, EarlyView.ABSTRACT Centrosomes catalyze the assembly of a microtubule‐based bipolar spindle, essential for the precise chromosome segregation during cell division. At the center of this process lies Polo‐Like Kinase 4 (PLK4), the master regulator that controls the duplication of the centriolar core to ensure the correct balance of two centrosomes per dividing ...
Muhammad Hamzah +2 more
wiley +1 more source
CeNDR, the Caenorhabditis elegans natural diversity resource
Nucleic Acids Res., 2016 Studies in model organisms have yielded considerable insights into the etiology of disease and our understanding of evolutionary processes. Caenorhabditis elegans is among the most powerful model organisms used to understand biology. However, C.
Daniel E. Cook +3 more
semanticscholar +1 more source
The NLS3 Motif in TPX2 Regulates Spindle Architecture in Xenopus Egg Extracts
Cytoskeleton, EarlyView.ABSTRACT A bipolar spindle composed of microtubules and many associated proteins functions to segregate chromosomes during cell division in all eukaryotes, yet both spindle size and architecture vary dramatically across different species and cell types.
Guadalupe E. Pena +4 more
wiley +1 more source
A new defense in the battle of the sexes
eLife, 2019 Young Caenorhabditis elegans hermaphrodites use their own sperm to protect against the negative consequences of mating.
George L Sutphin
doaj +1 more source
Assembly of the Caenorhabditis elegans gut microbiota from diverse soil microbial environments
The ISME Journal, 2016 It is now well accepted that the gut microbiota contributes to our health. However, what determines the microbiota composition is still unclear. Whereas it might be expected that the intestinal niche would be dominant in shaping the microbiota, studies ...
Maureen Berg +7 more
semanticscholar +1 more source
Unraveling the mechanisms of synapse formation and axon regeneration: the awesome power of C. elegans genetics. [PDF]
, 2015 Since Caenorhabditis elegans was chosen as a model organism by Sydney Brenner in 1960's, genetic studies in this organism have been instrumental in discovering the function of genes and in deciphering molecular signaling network.
Jin, YiShi
core +3 more sources
Developmental Dynamics, EarlyView.Abstract Background The endocannabinoid system is a neuromodulatory system implicated in cellular processes during both development and regeneration. The Mexican axolotl, one of only a few vertebrates capable of central nervous system regeneration, was used to examine the role of the endocannabinoid system in the regeneration of the tail and spinal ...
Michael Tolentino +3 more
wiley +1 more source