Results 111 to 120 of about 193,403 (293)

fog-2 and the evolution of self-fertile hermaphroditism in Caenorhabditis.

PLoS Biology, 2005
Somatic and germline sex determination pathways have diverged significantly in animals, making comparisons between taxa difficult. To overcome this difficulty, we compared the genes in the germline sex determination pathways of Caenorhabditis elegans and
Sudhir Nayak, Johnathan Goree, Tim Schedl   +2 more
doaj   +1 more source

Caenorhabditis elegans as a Model for Microbiome Research

Frontiers in Microbiology, 2017
The nematode Caenorhabditis elegans is used as a central model system across biological disciplines. Surprisingly, almost all research with this worm is performed in the absence of its native microbiome, possibly affecting generality of the obtained ...
Fan Zhang, Maureen Berg, Katja Dierking, M. Félix, M. Shapira, B. Samuel, H. Schulenburg   +6 more
semanticscholar   +1 more source

Uncovering New Functions for MicroRNAs in \u3cem\u3eCaenorhabditis elegans\u3c/em\u3e [PDF]

, 2011
In the race to understand microRNA (miRNA) functions in development and physiology, Caenorhabditis elegans investigators were the first out of the gate with the cloning and analysis of the lin-4 and let-7 miRNAs [1,2].
Abbott, Allison L.
core   +2 more sources

A novel transgenic reporter of extracellular acidification in zebrafish elucidates skeletal muscle T‐tubule pH regulation

Developmental Dynamics, EarlyView.
Abstract Disruption of extracellular pH and proton‐sensing can profoundly impact cellular and protein functions, leading to developmental defects. To visualize changes in extracellular pH in the developing embryo, we generated a zebrafish transgenic line that ubiquitously expresses the ratiometric pH‐sensitive fluorescent protein pHluorin2, tethered to
Leif R. Neitzel, Maya Silver, Aaron H. Wasserman, Samantha Rea, Charles C. Hong, Charles H. Williams   +5 more
wiley   +1 more source

Purple pitanga extract and loaded liposomes effects in a tumorous Caenorhabditis elegans model

Journal of Agriculture and Food Research
The Purple Pitanga Extract (PPE) demonstrated apoptotic and anti-cancer effects in previous studies with cells. Therefore, the investigation of specific pathways involved in the development of cancer using in vivo models is necessary.
Flávia Suelen de Oliveira Pereira, Gabriel Pedroso Viçozzi, Maria Eduarda Oliveira Souza, Andreia Limana Tambara, Félix Roman Munieweg, Sandra Elisa Haas, Elton Luís Gasparotto Denardin, Simone Pinton, Cristiane Casagrande Denardin, Daiana Silva Ávila   +9 more
doaj  

An evolutionarily conserved transcriptional response to viral infection in Caenorhabditis nematodes

BMC Genomics, 2017
Background Caenorhabditis elegans is a powerful model organism for probing many biological processes including host-pathogen interactions with bacteria and fungi. The recent identification of nematode viruses that naturally infect C.
Kevin Chen, Carl J. Franz, Hongbing Jiang, Yanfang Jiang, David Wang   +4 more
doaj   +1 more source

CRISPR-Based Methods for Caenorhabditis elegans Genome Engineering

Genetics, 2016
The advent of genome editing techniques based on the clustered regularly interspersed short palindromic repeats (CRISPR)–Cas9 system has revolutionized research in the biological sciences. CRISPR is quickly becoming an indispensible experimental tool for
D. Dickinson, B. Goldstein
semanticscholar   +1 more source

Most \u3cem\u3eCaenorhabditis elegans\u3c/em\u3e MicroRNAs are Individually Not Essential for Development or Viability [PDF]

, 2007
MicroRNAs (miRNAs), a large class of short noncoding RNAs found in many plants and animals, often act to post-transcriptionally inhibit gene expression. We report the generation of deletion mutations in 87 miRNA genes in Caenorhabditis elegans, expanding
Abbott, Allison L., Alvarez-Saavedra, Ezequiel, Ambros, Victor R., Bartel, David P., Hellman, Andrew B., Horvitz, H. Robert, Lau, Nelson C., McGonagle, Shannon M., Miska, Eric A.   +8 more
core   +1 more source

Bridging the Gap Between Human Toxicology and Ecotoxicology Under One Health Perspective by a Cross‐Species Adverse Outcome Pathway Network for Reproductive Toxicity

Environmental Toxicology and Chemistry, EarlyView.
Cross‐species extrapolation of adverse outcome pathway network on reproductive toxicity under the One Health perspective using new approach methodologies. AOP = adverse outcome pathway. Abstract Although ecotoxicological and toxicological risk assessments are performed separately from each other, recent efforts have been made in both disciplines to ...
Elizabeth Dufourcq Sekatcheff, Jaeseong Jeong, Jinhee Choi   +2 more
wiley   +1 more source

Survival assays using Caenorhabditis elegans

Molecules and Cells, 2017
Caenorhabditis elegans is an important model organism with many useful features, including rapid development and aging, easy cultivation, and genetic tractability. Survival assays using C. elegans are powerful methods for studying physiological processes.
Hae-Eun H. Park, Yoonji Jung, Seung-Jae V. Lee   +2 more
semanticscholar   +1 more source