Results 111 to 120 of about 279,189 (378)

DUPLICATIONS IN CAENORHABDITIS ELEGANS [PDF]

Genetics, 1979
ABSTRACT Thirteen chromosomal duplications, all unlinked to their linkage group of origin, have been identified following X-irradiation. Ten are X-chromosome duplications, of which six are half-translocations on three autosomomal linkage groups and four are free fragments.
Claire K. Kari, Robert K. Herman, J. E. Madl   +2 more
openaire   +3 more sources

Supramolecular Probe for Monitoring Lysosomal Ferritinophagy to Facilitate the Early Diagnosis of Parkinson's Disease

Aggregate, EarlyView.
A supramolecular fluorescent probe, TPE‐4B/4Q[7], was designed to target lysosomes. The restriction of intramolecular rotation effect mediated by Q[7] enhances the fluorescence of TPE‐4B/4Q[7], enabling selective detection of Fe3+ with a detection limit of 1.23 × 10⁻⁶ M.
Shiqin Zhou, Bo Xiao, Jiamin Chen, Jinming Zhu, Xia Ran, Zuoji Liu, Chaozhong Li, Li Wang, Xinai Cui, Rong Li, Guangwei Feng, Jian Feng   +11 more
wiley   +1 more source

Imaging the Pharynx to Measure the Uptake of Doxorubicin in Caenorhabditis elegans

Bio-Protocol, 2017
Caenorhabditis elegans offers an array of advantages to investigate the roles of uptake transporters. Herein, an epifluorescent microscopy approach was developed to monitor the uptake of the autofluorescent anticancer drug, doxorubicin, into the pharynx ...
Sivathevy Amirthagunabalasingam, Arturo Papaluca, Taramatti Harihar, Dindial Ramotar   +3 more
doaj   +1 more source

Histone deacetylase HDA-1 modulates mitochondrial stress response and longevity

Nature Communications, 2020
Caenorhabditis elegans responds to mitochondrial stress by activating the mitochondrial unfolded protein response (UPRmt). Here the authors show that HDA-1, the C.
Li-Wa Shao, Qi Peng, Mingyue Dong, Kaiyu Gao, Yumei Li, Yi Li, Chuan-Yun Li, Ying Liu   +7 more
doaj   +1 more source

Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk. [PDF]

, 2019
Genetic studies of complex traits in animals have been hindered by the need to generate, maintain, and phenotype large panels of recombinant lines. We developed a new method, C.
Ben-David, Eyal, Boocock, James, Burga, Alejandro, Kruglyak, Leonid, Lemus Vergara, Tzitziki   +4 more
core  

Long-range correlations and fractal dynamics in C. elegans: changes with aging and stress

, 2017
Reduced motor control is one of the most frequent features associated with aging and disease. Nonlinear and fractal analyses have proved to be useful in investigating human physiological alterations with age and disease.
Alves, Luiz G. A., Amaral, Luís A. N., Brielmann, Renée M., Ferreira, Leonardo N., Morimoto, Richard I., Winter, Peter B.   +5 more
core   +1 more source

The Natural Biotic Environment of Caenorhabditis elegans

Genetics, 2017
Organisms evolve in response to their natural environment. Consideration of natural ecological parameters are thus of key importance for our understanding of an organism’s biology.
H. Schulenburg, M. Félix
semanticscholar   +1 more source

Deep Learning‐Assisted Coherent Raman Scattering Microscopy

Advanced Intelligent Discovery, EarlyView.
The analytical capabilities of coherent Raman scattering microscopy are augmented through deep learning integration. This synergistic paradigm improves fundamental performance via denoising, deconvolution, and hyperspectral unmixing. Concurrently, it enhances downstream image analysis including subcellular localization, virtual staining, and clinical ...
Jianlin Liu, Rujia Liu, Xinyan Zhang, Xun Chen, Shuhua Yue   +4 more
wiley   +1 more source

Expanded genetic screening in Caenorhabditis elegans identifies new regulators and an inhibitory role for NAD+ in axon regeneration. [PDF]

, 2018
The mechanisms underlying axon regeneration in mature neurons are relevant to the understanding of normal nervous system maintenance and for developing therapeutic strategies for injury.
Andrusiak, Matthew G, Cherra, Salvatore J, Chisholm, Andrew D, Jin, Yishi, Kim, Kyung Won, Kurup, Naina, Park, Seungmee, Piggott, Christopher A, Tang, Ngang Heok, Wu, Zilu, Zhu, Ming   +10 more
core   +1 more source

The invertebrate Caenorhabditis elegans biosynthesizes ascorbate. [PDF]

, 2015
l-Ascorbate, commonly known as vitamin C, serves as an antioxidant and cofactor essential for many biological processes. Distinct ascorbate biosynthetic pathways have been established for animals and plants, but little is known about the presence or ...
Adler, Lital N, Budenholzer, Lauren M, Clarke, Steven G, Patananan, Alexander N, Pedraza, Maria E, Torres, Eric R   +5 more
core   +2 more sources