Results 141 to 150 of about 193,403 (293)
Molecular Nutrition &Food Research, EarlyView.Epicatechin and quercetin enhanced healthspan in the C. elegans BR5270 tauopathy model, associated with the upregulation of autophagy‐related and α‐tubulin synthesis genes, and the downregulation of genes involved in the unfolded protein response. ABSTRACT The prevalence of cognitive disorders such as Alzheimer's disease (AD) is increasing due to the ...
Lidia Garzón‐García +4 more
wiley +1 more source
Saudi Pharmaceutical Journal, 2021 The use of many psychotropic drugs (PDs) is associated with increased caloric intake, significant weight gain, and metabolic disorders. The nematode Caenorhabditis elegans (C. elegans) has been used to study the effects of PDs on food intake.
Abdullah Almotayri +5 more
doaj
GENETIC ORGANIZATION IN CAENORHABDITIS ELEGANS: FINE-STRUCTURE ANALYSIS OF THE unc-22 GENE [PDF]
, 1979 Donald G. Moerman, David L. Baillie
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Targeting gut microbiota as a therapeutic approach for neurodegenerative diseases
Neuroprotection, EarlyView.The abstract depicts the gut‐brain axis, illustrating the bidirectional communication between the gastrointestinal tract and the central nervous system. Probiotics can induce the production of neurotrophins, neurotransmitters, SCFAs, and contribute to increased antioxidant levels, which can benefit brain health. In contrast, antibiotics can disrupt the
Tobiloba S. Olajide +1 more
wiley +1 more source
A sterol-defined system for quantitative studies of sterol metabolism in C. elegans
STAR Protocols, 2021 Summary: This protocol describes the culturing of the nematode Caenorhabditis elegans (C. elegans) in a sterol-defined experimental system and the subsequent quantitative analysis of C.
Benjamin Trabelcy +2 more
doaj
LETHALS, STERILES AND DEFICIENCIES IN A REGION OF THE X CHROMOSOME OF CAENORHABDITIS ELEGANS [PDF]
, 1979 Philip Meneely, Robert K Herman
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The role of gut microbiota‐derived metabolites in neuroinflammation
Neuroprotection, EarlyView.Gut microbiota‐derived metabolites accumulate in the brain, activating or inhibiting microglia and astrocytes, which affects neuroinflammatory progression. The gut microbiota converts the diet into a variety of metabolites, including bile acid, trimethylamine N‑oxide (TMAO), and indole.
Lingjie Mu, Yijie Wang
wiley +1 more source
Top‐Down Proteomics: Why and When?
PROTEOMICS, EarlyView.ABSTRACT Manifold biological processes at all levels of transcription and translation can lead to the formation of a high number of different protein species (i.e., proteoforms), which outnumber the sequences encoded in the genome by far. Due to the large number of protein molecules formed in this way, which span an enormous range of different ...
Philipp T. Kaulich, Andreas Tholey
wiley +1 more source
Inappropriateness of RNAlater to preserve Caenorhabditis elegans for RNA extraction
MethodsX, 2019 Caenorhabditis elegans is a well-established laboratory animal model and has been widely used in biological research. However, it is still a challenge to obtain a good amount of quality RNA from a limited number of C. elegans for gene expression studies.
Leming Jiang +6 more
doaj
Nematicidal activity of Annona crassiflora leaf extract on Caenorhabditis elegans
Parasites & Vectors, 2015 Background The aim of this work was to investigate the potential nematicidal activity of Annona crassiflora leaf extract against Caenorhabditis elegans.
Alan Rodrigues Teixeira Machado +5 more
doaj +1 more source