Results 11 to 20 of about 193,403 (293)

Diversification of the Caenorhabditis heat shock response by Helitron transposable elements [PDF]

eLife, 2019
Heat Shock Factor 1 (HSF-1) is a key regulator of the heat shock response (HSR). Upon heat shock, HSF-1 binds well-conserved motifs, called Heat Shock Elements (HSEs), and drives expression of genes important for cellular protection during this stress ...
Jacob M Garrigues, Brian V Tsu, Matthew D Daugherty, Amy E Pasquinelli   +3 more
doaj   +4 more sources

Phenotypic covariance of longevity, immunity and stress resistance in the Caenorhabditis nematodes [PDF]

, 2010
Background \ud Ageing, immunity and stresstolerance are inherent characteristics of all organisms. In animals, these traits are regulated, at least in part, by forkhead transcription factors in response to upstream signals from the Insulin/Insulin– like ...
A Aballay, A Aballay, A Aballay, A Fodor, A Labrousse, AL O'Quinn, Ben Lehner, C Kenyon, CD Sifri, CL Kurz, Claudia M. L. Boehnisch, CT Murphy, CT Murphy, D Barsyte, D McCulloch, DA Garsin, DB Friedman, DJ Clancy, DL Riddle, DL Riddle, DW Huang, E Mylonakis, EA Evans, Francis R. G. Amrit, G Dennis, GWP Joshua, IA Hope, J Halaschek-Wiener, J McElwee, J Van Helden, JJ McElwee, JJ McElwee, K Kiontke, KD Kimura, KJ Livak, L Partridge, LA Gallagher, M Holzenberger, M Suyama, M Tatar, MA Larkin, MCWVD Berg, MN Patel, MQ Dong, MR Klass, RA Alegado, RC Cassada, Robin C. May, RYN Lee, S Brenner, S Murakami, SS Lee, ST Henderson, SW Oh, T Furuyama, T Inoue, TB Kirkwood, TH Galbadage, TMW G J Lithgow, VD Longo   +59 more
core   +19 more sources

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei, Elena Parrini, Claudia Bianchini, Maria Luisa Ricci, Renzo Guerrini   +4 more
wiley   +1 more source

The temporal scaling of Caenorhabditis elegans ageing

Nature, 2016
Nicholas Stroustrup, Javier Apfeld, Walter Fontana   +2 more
exaly   +2 more sources

DAF-16/FoxO in Caenorhabditis elegans and its role in metabolic remodeling [PDF]

, 2020
DAF-16, the only forkhead box transcription factors class O (FoxO) homolog in Caenorhabditis elegans, integrates signals from upstream pathways to elicit transcriptional changes in many genes involved in aging, development, stress, metabolism, and ...
Braeckman, Bart, Zečić, Aleksandra
core   +1 more source

Natural variation in reproductive timing and X-chromosome nondisjunction in Caenorhabditis elegans

G3: Genes, Genomes, Genetics, 2021
Caenorhabditis elegansC. elegansC.
Jiseon Lim, Jun Kim, Junho Lee
doaj   +1 more source

CeMbio - The Caenorhabditis elegans Microbiome Resource

G3, 2020
The study of microbiomes by sequencing has revealed a plethora of correlations between microbial community composition and various life-history characteristics of the corresponding host species.
P. Dirksen, Adrien Assié, J. Zimmermann, Fan Zhang, Adina-Malin Tietje, Sarah Arnaud Marsh, M. Félix, M. Shapira, C. Kaleta, H. Schulenburg, B. Samuel   +10 more
semanticscholar   +1 more source

WormBase 2007 [PDF]

, 2008
WormBase (www.wormbase.org) is the major publicly available database of information about Caenorhabditis elegans, an important system for basic biological and biomedical research. Derived from the initial ACeDB database of C. elegans genetic and sequence
A. Petcherski, A. Rogers, Ashburner, C. Bastiani, C. Nakamura, D. Blasiar, D. Wang, Deplancke, E. M. Schwarz, G. Schindelman, G. Williams, H.-M. Muller, Hillier, Husson, I. Antoshechkin, J. Chan, J. Fernandes, J. Spieth, K. Van Auken, K. Yook, Kirienko, L. D. Stein, Li, Li, M. A. Tuli, M. Han, Matera, Meyer, M  ller, O'Brien, P. Canaran, P. Davis, P. Ozersky, P. W. Sternberg, Potter, R. Durbin, R. Kishore, R. Lee, Ruby, S. McKay, T. Bieri, T. J. Fiedler, T. W. Harris, Tatusov, W. J. Chen, W. Spooner, Wachi, Walhout, X. Wang, Zemann, Zhang, Zhong   +51 more
core   +3 more sources

Deep sampling of Hawaiian Caenorhabditis elegans reveals high genetic diversity and admixture with global populations

eLife, 2019
Hawaiian isolates of the nematode species Caenorhabditis elegans have long been known to harbor genetic diversity greater than the rest of the worldwide population, but this observation was supported by only a small number of wild strains.
Tim A Crombie, Stefan Zdraljevic, Daniel E Cook, Robyn E Tanny, Shannon C Brady, Ye Wang, Kathryn S Evans, Steffen Hahnel, Daehan Lee, Briana C Rodriguez, Gaotian Zhang, Joost van der Zwagg, Karin Kiontke, Erik C Andersen   +13 more
doaj   +1 more source

CeAid: a smartphone application for logging and plotting Caenorhabditis elegans assays

G3: Genes, Genomes, Genetics, 2021
Caenorhabditis elegansC.
Salman Sohrabi, Rebecca S Moore, Coleen T Murphy   +2 more
doaj   +1 more source